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Sex- and age-dependent genetics of longevity in a heterogeneous mouse population.
Bou Sleiman M, Roy S, Gao AW, Sadler MC, von Alvensleben GVG, Li H, Sen S, Harrison DE, Nelson JF, Strong R, Miller RA, Kutalik Z, Williams RW, Auwerx J. Bou Sleiman M, et al. Among authors: williams rw. Science. 2022 Sep 30;377(6614):eabo3191. doi: 10.1126/science.abo3191. Epub 2022 Sep 30. Science. 2022. PMID: 36173858 Free PMC article.
Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, Häring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J. Koutnikova H, et al. Among authors: williams rw. PLoS Genet. 2009 Aug;5(8):e1000591. doi: 10.1371/journal.pgen.1000591. Epub 2009 Aug 7. PLoS Genet. 2009. PMID: 19662162 Free PMC article.
Metabolic networks of longevity.
Houtkooper RH, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: williams rw. Cell. 2010 Jul 9;142(1):9-14. doi: 10.1016/j.cell.2010.06.029. Cell. 2010. PMID: 20603007 Free PMC article.
Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits.
McKnite AM, Perez-Munoz ME, Lu L, Williams EG, Brewer S, Andreux PA, Bastiaansen JW, Wang X, Kachman SD, Auwerx J, Williams RW, Benson AK, Peterson DA, Ciobanu DC. McKnite AM, et al. Among authors: williams rw, williams eg. PLoS One. 2012;7(6):e39191. doi: 10.1371/journal.pone.0039191. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22723961 Free PMC article.
Mitonuclear protein imbalance as a conserved longevity mechanism.
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. Houtkooper RH, et al. Among authors: williams rw. Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188. Nature. 2013. PMID: 23698443 Free PMC article.
Genetics of gene expression in CNS.
Pandey AK, Williams RW. Pandey AK, et al. Among authors: williams rw. Int Rev Neurobiol. 2014;116:195-231. doi: 10.1016/B978-0-12-801105-8.00008-4. Int Rev Neurobiol. 2014. PMID: 25172476 Free PMC article. Review.
Joint mouse-human phenome-wide association to test gene function and disease risk.
Wang X, Pandey AK, Mulligan MK, Williams EG, Mozhui K, Li Z, Jovaisaite V, Quarles LD, Xiao Z, Huang J, Capra JA, Chen Z, Taylor WL, Bastarache L, Niu X, Pollard KS, Ciobanu DC, Reznik AO, Tishkov AV, Zhulin IB, Peng J, Nelson SF, Denny JC, Auwerx J, Lu L, Williams RW. Wang X, et al. Among authors: williams rw, williams eg. Nat Commun. 2016 Feb 2;7:10464. doi: 10.1038/ncomms10464. Nat Commun. 2016. PMID: 26833085 Free PMC article.
615 results