Williams CM - Search Results

1

A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase.

Jin DY, Chen X, Liu Y, Williams CM, Pedersen LC, Stafford DW, Tie JK. Jin DY, et al. Among authors: williams cm. Nat Commun. 2023 Feb 14;14(1):828. doi: 10.1038/s41467-023-36446-8. Nat Commun. 2023. PMID: 36788244 Free PMC article.

2

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement.

Xing H, Houston SD, Chen X, Ghassabian S, Fahrenhorst-Jones T, Kuo A, Murray CP, Conn KA, Jaeschke KN, Jin DY, Pasay C, Bernhardt PV, Burns JM, Tsanaktsidis J, Savage GP, Boyle GM, De Voss JJ, McCarthy J, Walter GH, Burne THJ, Smith MT, Tie JK, Williams CM. Xing H, et al. Among authors: williams cm. Chemistry. 2019 Feb 21;25(11):2729-2734. doi: 10.1002/chem.201806277. Epub 2019 Jan 25. Chemistry. 2019. PMID: 30681236 Free PMC article.

3

Determining the necessity of phenyl ring π-character in warfarin.

Xing H, Houston SD, Chen X, Jin DY, Savage GP, Tie JK, Williams CM. Xing H, et al. Among authors: williams cm. Bioorg Med Chem Lett. 2019 Aug 1;29(15):1954-1956. doi: 10.1016/j.bmcl.2019.05.039. Epub 2019 May 23. Bioorg Med Chem Lett. 2019. PMID: 31147103 Free PMC article.

4

A novel vitamin K derived anticoagulant tolerant to genetic variations of vitamin K epoxide reductase.

Chen X, Liu Y, Furukawa N, Jin DY, Paul Savage G, Stafford DW, Suhara Y, Williams CM, Tie JK. Chen X, et al. Among authors: williams cm. J Thromb Haemost. 2021 Mar;19(3):689-700. doi: 10.1111/jth.15209. Epub 2021 Jan 22. J Thromb Haemost. 2021. PMID: 33314621 Free PMC article.

5

Naturally occurring UBIAD1 mutations differentially affect menaquinone biosynthesis and vitamin K-dependent carboxylation.

Chen X, Furukawa N, Jin DY, Liu Y, Stafford DW, Williams CM, Suhara Y, Tie JK. Chen X, et al. Among authors: williams cm. FEBS J. 2022 May;289(9):2613-2627. doi: 10.1111/febs.16291. Epub 2021 Dec 1. FEBS J. 2022. PMID: 34813684 Free PMC article.

6

Structural basis of resistance to herbicides that target acetohydroxyacid synthase.

Lonhienne T, Cheng Y, Garcia MD, Hu SH, Low YS, Schenk G, Williams CM, Guddat LW. Lonhienne T, et al. Among authors: williams cm. Nat Commun. 2022 Jun 11;13(1):3368. doi: 10.1038/s41467-022-31023-x. Nat Commun. 2022. PMID: 35690625 Free PMC article.

7

Structures of fungal and plant acetohydroxyacid synthases.

Lonhienne T, Low YS, Garcia MD, Croll T, Gao Y, Wang Q, Brillault L, Williams CM, Fraser JA, McGeary RP, West NP, Landsberg MJ, Rao Z, Schenk G, Guddat LW. Lonhienne T, et al. Among authors: williams cm. Nature. 2020 Oct;586(7828):317-321. doi: 10.1038/s41586-020-2514-3. Epub 2020 Jul 8. Nature. 2020. PMID: 32640464

8

A concise total synthesis of (±)-cipadonoid B from synthetic azedaralide.

Faber JM, Williams CM. Faber JM, et al. Among authors: williams cm. Chem Commun (Camb). 2011 Feb 28;47(8):2258-60. doi: 10.1039/c0cc04698a. Epub 2011 Jan 24. Chem Commun (Camb). 2011. PMID: 21258734

9

Enantioselective total synthesis of (-)-neovibsanin G and (-)-14-epi-neovibsanin G.

Mak JY, Williams CM. Mak JY, et al. Among authors: williams cm. Chem Commun (Camb). 2012 Jan 7;48(2):287-9. doi: 10.1039/c1cc15995j. Epub 2011 Nov 18. Chem Commun (Camb). 2012. PMID: 22101234

10

N-Oxides rescue Ru(v) in catalytic Griffith-Ley (TPAP) alcohol oxidations.

Zerk TJ, Moore PW, Williams CM, Bernhardt PV. Zerk TJ, et al. Among authors: williams cm. Chem Commun (Camb). 2016 Aug 11;52(67):10301-4. doi: 10.1039/c6cc05440d. Chem Commun (Camb). 2016. PMID: 27471846

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