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Non-cytotoxic 1,2,3-triazole tethered fused heterocyclic ring derivatives display Tax protein inhibition and impair HTLV-1 infected cells.
Dos Santos DF, de Pilger DRB, Vandermeulen C, Khouri R, Mantoani SP, Nunes PSG, de Andrade P, Carvalho I, Casseb J, Twizere JC, Willems L, Freitas-Junior L, Kashima S. Dos Santos DF, et al. Among authors: willems l. Bioorg Med Chem. 2020 Nov 15;28(22):115746. doi: 10.1016/j.bmc.2020.115746. Epub 2020 Sep 8. Bioorg Med Chem. 2020. PMID: 33007558
Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression.
Twizere JC, Kruys V, Lefèbvre L, Vanderplasschen A, Collete D, Debacq C, Lai WS, Jauniaux JC, Bernstein LR, Semmes OJ, Burny A, Blackshear PJ, Kettmann R, Willems L. Twizere JC, et al. Among authors: willems l. J Natl Cancer Inst. 2003 Dec 17;95(24):1846-59. doi: 10.1093/jnci/djg118. J Natl Cancer Inst. 2003. PMID: 14679154 Free article.
Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.
Twizere JC, Springael JY, Boxus M, Burny A, Dequiedt F, Dewulf JF, Duchateau J, Portetelle D, Urbain P, Van Lint C, Green PL, Mahieux R, Parmentier M, Willems L, Kettmann R. Twizere JC, et al. Among authors: willems l. Blood. 2007 Feb 1;109(3):1051-60. doi: 10.1182/blood-2006-06-026781. Epub 2006 Sep 21. Blood. 2007. PMID: 16990599 Free PMC article.
Cell dynamics and immune response to BLV infection: a unifying model.
Florins A, Gillet N, Asquith B, Boxus M, Burteau C, Twizere JC, Urbain P, Vandermeers F, Debacq C, Sanchez-Alcaraz MT, Schwartz-Cornil I, Kerkhofs P, Jean G, Théwis A, Hay J, Mortreux F, Wattel E, Reichert M, Burny A, Kettmann R, Bangham C, Willems L. Florins A, et al. Among authors: willems l. Front Biosci. 2007 Jan 1;12:1520-31. doi: 10.2741/2165. Front Biosci. 2007. PMID: 17127399 Free article. Review.
The HTLV-1 Tax interactome.
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L. Boxus M, et al. Among authors: willems l. Retrovirology. 2008 Aug 14;5:76. doi: 10.1186/1742-4690-5-76. Retrovirology. 2008. PMID: 18702816 Free PMC article. Review.
598 results