Wichelhaus TA - Search Results

1

Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases.

Büttner D, Kramer JS, Klingler FM, Wittmann SK, Hartmann MR, Kurz CG, Kohnhäuser D, Weizel L, Brüggerhoff A, Frank D, Steinhilber D, Wichelhaus TA, Pogoryelov D, Proschak E. Büttner D, et al. Among authors: wichelhaus ta. ACS Infect Dis. 2018 Mar 9;4(3):360-372. doi: 10.1021/acsinfecdis.7b00129. Epub 2017 Dec 12. ACS Infect Dis. 2018. PMID: 29172434

2

Multistep virtual screening for rapid and efficient identification of non-nucleoside bacterial thymidine kinase inhibitors.

Zander J, Hartenfeller M, Hähnke V, Proschak E, Besier S, Wichelhaus TA, Schneider G. Zander J, et al. Among authors: wichelhaus ta. Chemistry. 2010 Aug 16;16(31):9630-7. doi: 10.1002/chem.201001347. Chemistry. 2010. PMID: 20648496

3

Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.

Klingler FM, Wichelhaus TA, Frank D, Cuesta-Bernal J, El-Delik J, Müller HF, Sjuts H, Göttig S, Koenigs A, Pos KM, Pogoryelov D, Proschak E. Klingler FM, et al. Among authors: wichelhaus ta. J Med Chem. 2015 Apr 23;58(8):3626-30. doi: 10.1021/jm501844d. Epub 2015 Apr 13. J Med Chem. 2015. PMID: 25815530

4

Correction to Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria.

Klingler FM, Wichelhaus TA, Frank D, Cuesta-Bernal J, El-Delik J, Müller HF, Sjuts H, Göttig S, Koenigs A, Pos KM, Pogoryelov D, Proschak E. Klingler FM, et al. Among authors: wichelhaus ta. J Med Chem. 2015 Aug 13;58(15):6320. doi: 10.1021/acs.jmedchem.5b01097. Epub 2015 Jul 30. J Med Chem. 2015. PMID: 26225625 No abstract available.

5

Probing metallo-β-lactamases with molecular fragments identified by consensus docking.

Klingler FM, Moser D, Büttner D, Wichelhaus TA, Löhr F, Dötsch V, Proschak E. Klingler FM, et al. Among authors: wichelhaus ta. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5243-6. doi: 10.1016/j.bmcl.2015.09.056. Epub 2015 Sep 28. Bioorg Med Chem Lett. 2015. PMID: 26463134

6

CipA of Acinetobacter baumannii Is a Novel Plasminogen Binding and Complement Inhibitory Protein.

Koenigs A, Stahl J, Averhoff B, Göttig S, Wichelhaus TA, Wallich R, Zipfel PF, Kraiczy P. Koenigs A, et al. Among authors: wichelhaus ta. J Infect Dis. 2016 May 1;213(9):1388-99. doi: 10.1093/infdis/jiv601. Epub 2015 Dec 17. J Infect Dis. 2016. PMID: 26681776

7

Bacterial zincophore [S,S]-ethylenediamine-N,N'-disuccinic acid is an effective inhibitor of MBLs.

Proschak A, Kramer J, Proschak E, Wichelhaus TA. Proschak A, et al. Among authors: wichelhaus ta. J Antimicrob Chemother. 2018 Feb 1;73(2):425-430. doi: 10.1093/jac/dkx403. J Antimicrob Chemother. 2018. PMID: 29186432

8

Anti-tubercular activity of a natural stilbene and its synthetic derivatives.

Reinheimer C, Büttner D, Proschak E, Bode HB, Kempf VAJ, Wichelhaus TA. Reinheimer C, et al. Among authors: wichelhaus ta. GMS Infect Dis. 2018 Feb 1;6:Doc01. doi: 10.3205/id000036. eCollection 2018. GMS Infect Dis. 2018. PMID: 30671332 Free PMC article.

9

Emergence of ceftazidime/avibactam resistance in KPC-3-producing Klebsiella pneumoniae in vivo.

Göttig S, Frank D, Mungo E, Nolte A, Hogardt M, Besier S, Wichelhaus TA. Göttig S, et al. Among authors: wichelhaus ta. J Antimicrob Chemother. 2019 Nov 1;74(11):3211-3216. doi: 10.1093/jac/dkz330. J Antimicrob Chemother. 2019. PMID: 31365094

10

Rh^II -Catalyzed De-symmetrization of Ethane-1,2-dithiol and Propane-1,3-dithiol Yields Metallo-β-lactamase Inhibitors.

Krasavin M, Zhukovsky D, Solovyev I, Barkhatova D, Dar'in D, Frank D, Martinelli G, Weizel L, Proschak A, Rotter M, Kramer JS, Brunst S, Wichelhaus TA, Proschak E. Krasavin M, et al. Among authors: wichelhaus ta. ChemMedChem. 2021 Nov 19;16(22):3410-3417. doi: 10.1002/cmdc.202100344. Epub 2021 Aug 3. ChemMedChem. 2021. PMID: 34184833 Free PMC article.

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