Wei J - Search Results

1

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, Ni T, Zhang ZS, Zhang T, Li C, Han L, Zhu Z, Lian F, Wei J, Deng Q, Wang Y, Wunderlich M, Gao Z, Pan G, Zhong D, Zhou H, Zhang N, Gan J, Jiang H, Mulloy JC, Qian Z, Chen J, Yang CG. Huang Y, et al. Among authors: wei j. Cancer Cell. 2019 Apr 15;35(4):677-691.e10. doi: 10.1016/j.ccell.2019.03.006. Cancer Cell. 2019. PMID: 30991027 Free PMC article.

2

Differential m⁶A, m⁶A_m, and m¹A Demethylation Mediated by FTO in the Cell Nucleus and Cytoplasm.

Wei J, Liu F, Lu Z, Fei Q, Ai Y, He PC, Shi H, Cui X, Su R, Klungland A, Jia G, Chen J, He C. Wei J, et al. Mol Cell. 2018 Sep 20;71(6):973-985.e5. doi: 10.1016/j.molcel.2018.08.011. Epub 2018 Sep 6. Mol Cell. 2018. PMID: 30197295 Free PMC article.

3

m⁶A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade.

Yang S, Wei J, Cui YH, Park G, Shah P, Deng Y, Aplin AE, Lu Z, Hwang S, He C, He YY. Yang S, et al. Among authors: wei j. Nat Commun. 2019 Jun 25;10(1):2782. doi: 10.1038/s41467-019-10669-0. Nat Commun. 2019. PMID: 31239444 Free PMC article.

4

Autophagy of the m⁶A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis.

Cui YH, Yang S, Wei J, Shea CR, Zhong W, Wang F, Shah P, Kibriya MG, Cui X, Ahsan H, He C, He YY. Cui YH, et al. Among authors: wei j. Nat Commun. 2021 Apr 12;12(1):2183. doi: 10.1038/s41467-021-22469-6. Nat Commun. 2021. PMID: 33846348 Free PMC article.

5

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.

Yu F, Wei J, Cui X, Yu C, Ni W, Bungert J, Wu L, He C, Qian Z. Yu F, et al. Among authors: wei j. Nucleic Acids Res. 2021 Jun 4;49(10):5779-5797. doi: 10.1093/nar/gkab415. Nucleic Acids Res. 2021. PMID: 34048572 Free PMC article.

6

A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication.

Sheng Y, Wei J, Yu F, Xu H, Yu C, Wu Q, Liu Y, Li L, Cui XL, Gu X, Shen B, Li W, Huang Y, Bhaduri-McIntosh S, He C, Qian Z. Sheng Y, et al. Among authors: wei j. Blood. 2021 Dec 30;138(26):2838-2852. doi: 10.1182/blood.2021011707. Blood. 2021. PMID: 34255814 Free PMC article.

7

METTL16 exerts an m⁶A-independent function to facilitate translation and tumorigenesis.

Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J. Su R, et al. Among authors: wei j. Nat Cell Biol. 2022 Feb;24(2):205-216. doi: 10.1038/s41556-021-00835-2. Epub 2022 Feb 10. Nat Cell Biol. 2022. PMID: 35145225 Free PMC article.

8

m⁶A RNA modifications are measured at single-base resolution across the mammalian transcriptome.

Hu L, Liu S, Peng Y, Ge R, Su R, Senevirathne C, Harada BT, Dai Q, Wei J, Zhang L, Hao Z, Luo L, Wang H, Wang Y, Luo M, Chen M, Chen J, He C. Hu L, et al. Among authors: wei j. Nat Biotechnol. 2022 Aug;40(8):1210-1219. doi: 10.1038/s41587-022-01243-z. Epub 2022 Mar 14. Nat Biotechnol. 2022. PMID: 35288668 Free PMC article.

9

FTO mediates LINE1 m⁶A demethylation and chromatin regulation in mESCs and mouse development.

Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C. Wei J, et al. Science. 2022 May 27;376(6596):968-973. doi: 10.1126/science.abe9582. Epub 2022 May 5. Science. 2022. PMID: 35511947 Free PMC article.

10

Author Correction: m⁶A RNA modifications are measured at single-base resolution across the mammalian transcriptome.

Hu L, Liu S, Peng Y, Ge R, Su R, Senevirathne C, Harada BT, Dai Q, Wei J, Zhang L, Hao Z, Luo L, Wang H, Wang Y, Luo M, Chen M, Chen J, He C. Hu L, et al. Among authors: wei j. Nat Biotechnol. 2023 Jan;41(1):150. doi: 10.1038/s41587-022-01616-4. Nat Biotechnol. 2023. PMID: 36450851 No abstract available.

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