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Neutrophils: Between host defence, immune modulation, and tissue injury.
Kruger P, Saffarzadeh M, Weber AN, Rieber N, Radsak M, von Bernuth H, Benarafa C, Roos D, Skokowa J, Hartl D. Kruger P, et al. PLoS Pathog. 2015 Mar 12;11(3):e1004651. doi: 10.1371/journal.ppat.1004651. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25764063 Free PMC article. Review.
The Bruton tyrosine kinase inhibitor ibrutinib abrogates triggering receptor on myeloid cells 1-mediated neutrophil activation.
Stadler N, Hasibeder A, Lopez PA, Teschner D, Desuki A, Kriege O, Weber ANR, Schulz C, Michel C, Heβ G, Radsak MP. Stadler N, et al. Among authors: weber anr. Haematologica. 2017 May;102(5):e191-e194. doi: 10.3324/haematol.2016.152017. Epub 2017 Jan 25. Haematologica. 2017. PMID: 28126969 Free PMC article. No abstract available.
Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.
Liu X, Pichulik T, Wolz OO, Dang TM, Stutz A, Dillen C, Delmiro Garcia M, Kraus H, Dickhöfer S, Daiber E, Münzenmayer L, Wahl S, Rieber N, Kümmerle-Deschner J, Yazdi A, Franz-Wachtel M, Macek B, Radsak M, Vogel S, Schulte B, Walz JS, Hartl D, Latz E, Stilgenbauer S, Grimbacher B, Miller L, Brunner C, Wolz C, Weber ANR. Liu X, et al. Among authors: weber anr. J Allergy Clin Immunol. 2017 Oct;140(4):1054-1067.e10. doi: 10.1016/j.jaci.2017.01.017. Epub 2017 Feb 16. J Allergy Clin Immunol. 2017. PMID: 28216434
The fungal ligand chitin directly binds TLR2 and triggers inflammation dependent on oligomer size.
Fuchs K, Cardona Gloria Y, Wolz OO, Herster F, Sharma L, Dillen CA, Täumer C, Dickhöfer S, Bittner Z, Dang TM, Singh A, Haischer D, Schlöffel MA, Koymans KJ, Sanmuganantham T, Krach M, Roger T, Le Roy D, Schilling NA, Frauhammer F, Miller LS, Nürnberger T, LeibundGut-Landmann S, Gust AA, Macek B, Frank M, Gouttefangeas C, Dela Cruz CS, Hartl D, Weber AN. Fuchs K, et al. EMBO Rep. 2018 Dec;19(12):e46065. doi: 10.15252/embr.201846065. Epub 2018 Oct 18. EMBO Rep. 2018. PMID: 30337494 Free PMC article.
Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis.
Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR. Herster F, et al. Among authors: weber anr. Front Immunol. 2019 Aug 16;10:1867. doi: 10.3389/fimmu.2019.01867. eCollection 2019. Front Immunol. 2019. PMID: 31474979 Free PMC article.
Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells.
El Maadidi S, Weber ANR, Motshwene P, Schüssler JM, Backes D, Dickhöfer S, Wang H, Liu X, Garcia MD, Taumer C, Soufi B, Wolz OO, Klimosch SN, Franz-Wachtel M, Macek B, Gay NJ. El Maadidi S, et al. Among authors: weber anr. Sci Rep. 2019 Sep 11;9(1):13168. doi: 10.1038/s41598-019-49017-z. Sci Rep. 2019. PMID: 31511529 Free PMC article.
Staphylococcus aureus Skin Colonization Is Enhanced by the Interaction of Neutrophil Extracellular Traps with Keratinocytes.
Bitschar K, Staudenmaier L, Klink L, Focken J, Sauer B, Fehrenbacher B, Herster F, Bittner Z, Bleul L, Schaller M, Wolz C, Weber ANR, Peschel A, Schittek B. Bitschar K, et al. Among authors: weber anr. J Invest Dermatol. 2020 May;140(5):1054-1065.e4. doi: 10.1016/j.jid.2019.10.017. Epub 2019 Dec 17. J Invest Dermatol. 2020. PMID: 31857094 Free article.
80 results