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Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. Alsamman S, et al. Among authors: weaver vm. Sci Transl Med. 2020 Aug 19;12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. Sci Transl Med. 2020. PMID: 32817366 Free PMC article.
Tissue mechanics, an important regulator of development and disease.
Ayad NME, Kaushik S, Weaver VM. Ayad NME, et al. Among authors: weaver vm. Philos Trans R Soc Lond B Biol Sci. 2019 Aug 19;374(1779):20180215. doi: 10.1098/rstb.2018.0215. Epub 2019 Jul 1. Philos Trans R Soc Lond B Biol Sci. 2019. PMID: 31431174 Free PMC article. Review.
Tension in tumour cells keeps metabolism high.
Ayad NME, Weaver VM. Ayad NME, et al. Among authors: weaver vm. Nature. 2020 Feb;578(7796):517-518. doi: 10.1038/d41586-020-00314-y. Nature. 2020. PMID: 32094916 No abstract available.
The extracellular matrix at a glance.
Frantz C, Stewart KM, Weaver VM. Frantz C, et al. Among authors: weaver vm. J Cell Sci. 2010 Dec 15;123(Pt 24):4195-200. doi: 10.1242/jcs.023820. J Cell Sci. 2010. PMID: 21123617 Free PMC article. Review. No abstract available.
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Laklai H, et al. Among authors: weaver vm. Nat Med. 2016 May;22(5):497-505. doi: 10.1038/nm.4082. Epub 2016 Apr 18. Nat Med. 2016. PMID: 27089513 Free PMC article.
Membrane Tension Locks In Pluripotency.
Muncie JM, Weaver VM. Muncie JM, et al. Among authors: weaver vm. Cell Stem Cell. 2021 Feb 4;28(2):175-176. doi: 10.1016/j.stem.2021.01.008. Cell Stem Cell. 2021. PMID: 33545073 Free article.
236 results