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Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47.
Huang C, Wang X, Wang Y, Feng Y, Wang X, Chen S, Yan P, Liao J, Zhang Q, Mao C, Li Y, Wang L, Wang X, Yi W, Cai W, Chen S, Hong N, He W, Chen J, Jin W. Huang C, et al. Among authors: wang x, wang l, wang y. Nat Cancer. 2024 Mar;5(3):500-516. doi: 10.1038/s43018-023-00691-z. Epub 2024 Jan 10. Nat Cancer. 2024. PMID: 38200243
Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.
Mei Y, Wang X, Zhang J, Liu D, He J, Huang C, Liao J, Wang Y, Feng Y, Li H, Liu X, Chen L, Yi W, Chen X, Bai HM, Wang X, Li Y, Wang L, Liang Z, Ren X, Qiu L, Hui Y, Zhang Q, Leng Q, Chen J, Jia G. Mei Y, et al. Among authors: wang x, wang l, wang y. Nat Cancer. 2023 Sep;4(9):1273-1291. doi: 10.1038/s43018-023-00598-9. Epub 2023 Jul 17. Nat Cancer. 2023. PMID: 37460871
SIRPα: A key player in innate immunity.
Feng Y, Huang C, Wang Y, Chen J. Feng Y, et al. Among authors: wang y. Eur J Immunol. 2023 Nov;53(11):e2350375. doi: 10.1002/eji.202350375. Epub 2023 Sep 17. Eur J Immunol. 2023. PMID: 37672390 Review.
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