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Homology-mediated end joining-based targeted integration using CRISPR/Cas9.
Yao X, Wang X, Hu X, Liu Z, Liu J, Zhou H, Shen X, Wei Y, Huang Z, Ying W, Wang Y, Nie YH, Zhang CC, Li S, Cheng L, Wang Q, Wu Y, Huang P, Sun Q, Shi L, Yang H. Yao X, et al. Among authors: wang x, wang y, wang q. Cell Res. 2017 Jun;27(6):801-814. doi: 10.1038/cr.2017.76. Epub 2017 May 19. Cell Res. 2017. PMID: 28524166 Free PMC article.
One-step generation of complete gene knockout mice and monkeys by CRISPR/Cas9-mediated gene editing with multiple sgRNAs.
Zuo E, Cai YJ, Li K, Wei Y, Wang BA, Sun Y, Liu Z, Liu J, Hu X, Wei W, Huo X, Shi L, Tang C, Liang D, Wang Y, Nie YH, Zhang CC, Yao X, Wang X, Zhou C, Ying W, Wang Q, Chen RC, Shen Q, Xu GL, Li J, Sun Q, Xiong ZQ, Yang H. Zuo E, et al. Among authors: wang x, wang ba, wang y, wang q. Cell Res. 2017 Jul;27(7):933-945. doi: 10.1038/cr.2017.81. Epub 2017 Jun 6. Cell Res. 2017. PMID: 28585534 Free PMC article.
Disruption of splicing-regulatory elements using CRISPR/Cas9 to rescue spinal muscular atrophy in human iPSCs and mice.
Li JJ, Lin X, Tang C, Lu YQ, Hu X, Zuo E, Li H, Ying W, Sun Y, Lai LL, Chen HZ, Guo XX, Zhang QJ, Wu S, Zhou C, Shen X, Wang Q, Lin MT, Ma LX, Wang N, Krainer AR, Shi L, Yang H, Chen WJ. Li JJ, et al. Among authors: wang n, wang q. Natl Sci Rev. 2019 Sep 3;7(1):92-101. doi: 10.1093/nsr/nwz131. eCollection 2020 Jan. Natl Sci Rev. 2019. PMID: 34691481 Free PMC article.
High-fidelity Cas13 variants for targeted RNA degradation with minimal collateral effects.
Tong H, Huang J, Xiao Q, He B, Dong X, Liu Y, Yang X, Han D, Wang Z, Wang X, Ying W, Zhang R, Wei Y, Xu C, Zhou Y, Li Y, Cai M, Wang Q, Xue M, Li G, Fang K, Zhang H, Yang H. Tong H, et al. Among authors: wang x, wang z, wang q. Nat Biotechnol. 2023 Jan;41(1):108-119. doi: 10.1038/s41587-022-01419-7. Epub 2022 Aug 11. Nat Biotechnol. 2023. PMID: 35953673
A comprehensive AI model development framework for consistent Gleason grading.
Huo X, Ong KH, Lau KW, Gole L, Young DM, Tan CL, Zhu X, Zhang C, Zhang Y, Li L, Han H, Lu H, Zhang J, Hou J, Zhao H, Gan H, Yin L, Wang X, Chen X, Lv H, Cao H, Yu X, Shi Y, Huang Z, Marini G, Xu J, Liu B, Chen B, Wang Q, Gui K, Shi W, Sun Y, Chen W, Cao D, Sanders SJ, Lee HK, Hue SS, Yu W, Tan SY. Huo X, et al. Among authors: wang q. Commun Med (Lond). 2024 May 9;4(1):84. doi: 10.1038/s43856-024-00502-1. Commun Med (Lond). 2024. PMID: 38724730
Genotypic analysis of RTS,S/AS01E malaria vaccine efficacy against parasite infection as a function of dosage regimen and baseline malaria infection status in children aged 5-17 months in Ghana and Kenya: a longitudinal phase 2b randomised controlled trial.
Juraska M, Early AM, Li L, Schaffner SF, Lievens M, Khorgade A, Simpkins B, Hejazi NS, Benkeser D, Wang Q, Mercer LD, Adjei S, Agbenyega T, Anderson S, Ansong D, Bii DK, Buabeng PBY, English S, Fitzgerald N, Grimsby J, Kariuki SK, Otieno K, Roman F, Samuels AM, Westercamp N, Ockenhouse CF, Ofori-Anyinam O, Lee CK, MacInnis BL, Wirth DF, Gilbert PB, Neafsey DE. Juraska M, et al. Among authors: wang q. Lancet Infect Dis. 2024 May 6:S1473-3099(24)00179-8. doi: 10.1016/S1473-3099(24)00179-8. Online ahead of print. Lancet Infect Dis. 2024. PMID: 38723650
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