Wang LX - Search Results

1

Synthetic nanobodies as tools to distinguish IgG Fc glycoforms.

Kao KS, Gupta A, Zong G, Li C, Kerschbaumer I, Borghi S, Achkar JM, Bournazos S, Wang LX, Ravetch JV. Kao KS, et al. Among authors: wang lx. Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2212658119. doi: 10.1073/pnas.2212658119. Epub 2022 Nov 21. Proc Natl Acad Sci U S A. 2022. PMID: 36409896 Free PMC article.

2

Chemoenzymatic synthesis and Fcγ receptor binding of homogeneous glycoforms of antibody Fc domain. Presence of a bisecting sugar moiety enhances the affinity of Fc to FcγIIIa receptor.

Zou G, Ochiai H, Huang W, Yang Q, Li C, Wang LX. Zou G, et al. Among authors: wang lx. J Am Chem Soc. 2011 Nov 23;133(46):18975-91. doi: 10.1021/ja208390n. Epub 2011 Nov 1. J Am Chem Soc. 2011. PMID: 22004528 Free PMC article.

3

Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies.

Trastoy B, Lomino JV, Pierce BG, Carter LG, Günther S, Giddens JP, Snyder GA, Weiss TM, Weng Z, Wang LX, Sundberg EJ. Trastoy B, et al. Among authors: wang lx. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6714-9. doi: 10.1073/pnas.1322908111. Epub 2014 Apr 21. Proc Natl Acad Sci U S A. 2014. PMID: 24753590 Free PMC article.

4

Structural characterization of anti-inflammatory immunoglobulin G Fc proteins.

Ahmed AA, Giddens J, Pincetic A, Lomino JV, Ravetch JV, Wang LX, Bjorkman PJ. Ahmed AA, et al. Among authors: wang lx. J Mol Biol. 2014 Sep 9;426(18):3166-3179. doi: 10.1016/j.jmb.2014.07.006. Epub 2014 Jul 15. J Mol Biol. 2014. PMID: 25036289 Free PMC article.

5

Endoglycosidases for the Synthesis of Polysaccharides and Glycoconjugates.

Li C, Wang LX. Li C, et al. Among authors: wang lx. Adv Carbohydr Chem Biochem. 2016;73:73-116. doi: 10.1016/bs.accb.2016.07.001. Epub 2016 Aug 23. Adv Carbohydr Chem Biochem. 2016. PMID: 27816108 Free PMC article. Review.

6

Modulating IgG effector function by Fc glycan engineering.

Li T, DiLillo DJ, Bournazos S, Giddens JP, Ravetch JV, Wang LX. Li T, et al. Among authors: wang lx. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3485-3490. doi: 10.1073/pnas.1702173114. Epub 2017 Mar 13. Proc Natl Acad Sci U S A. 2017. PMID: 28289219 Free PMC article.

7

Designer α1,6-Fucosidase Mutants Enable Direct Core Fucosylation of Intact N-Glycopeptides and N-Glycoproteins.

Li C, Zhu S, Ma C, Wang LX. Li C, et al. Among authors: wang lx. J Am Chem Soc. 2017 Oct 25;139(42):15074-15087. doi: 10.1021/jacs.7b07906. Epub 2017 Oct 16. J Am Chem Soc. 2017. PMID: 28990779 Free PMC article.

8

Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies.

Li T, Li C, Quan DN, Bentley WE, Wang LX. Li T, et al. Among authors: wang lx. Carbohydr Res. 2018 Mar 22;458-459:77-84. doi: 10.1016/j.carres.2018.02.007. Epub 2018 Feb 15. Carbohydr Res. 2018. PMID: 29475193 Free PMC article.

9

Top-Down Chemoenzymatic Approach to Synthesizing Diverse High-Mannose N-Glycans and Related Neoglycoproteins for Carbohydrate Microarray Analysis.

Toonstra C, Wu L, Li C, Wang D, Wang LX. Toonstra C, et al. Among authors: wang lx, wang d. Bioconjug Chem. 2018 Jun 20;29(6):1911-1921. doi: 10.1021/acs.bioconjchem.8b00145. Epub 2018 May 22. Bioconjug Chem. 2018. PMID: 29738673 Free PMC article.

10

Generation and Comparative Kinetic Analysis of New Glycosynthase Mutants from Streptococcus pyogenes Endoglycosidases for Antibody Glycoengineering.

Tong X, Li T, Li C, Wang LX. Tong X, et al. Among authors: wang lx. Biochemistry. 2018 Sep 4;57(35):5239-5246. doi: 10.1021/acs.biochem.8b00719. Epub 2018 Aug 22. Biochemistry. 2018. PMID: 30102520 Free PMC article.

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