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Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Runtsch MC, Angiari S, Hooftman A, Wadhwa R, Zhang Y, Zheng Y, Spina JS, Ruzek MC, Argiriadi MA, McGettrick AF, Mendez RS, Zotta A, Peace CG, Walsh A, Chirillo R, Hams E, Fallon PG, Jayamaran R, Dua K, Brown AC, Kim RY, Horvat JC, Hansbro PM, Wang C, O'Neill LAJ. Runtsch MC, et al. Among authors: wadhwa r. Cell Metab. 2022 Mar 1;34(3):487-501.e8. doi: 10.1016/j.cmet.2022.02.002. Cell Metab. 2022. PMID: 35235776 Free article.
Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: An emerging need for novel drug delivery systems.
Dua K, Malyla V, Singhvi G, Wadhwa R, Krishna RV, Shukla SD, Shastri MD, Chellappan DK, Maurya PK, Satija S, Mehta M, Gulati M, Hansbro N, Collet T, Awasthi R, Gupta G, Hsu A, Hansbro PM. Dua K, et al. Among authors: wadhwa r. Chem Biol Interact. 2019 Feb 1;299:168-178. doi: 10.1016/j.cbi.2018.12.009. Epub 2018 Dec 13. Chem Biol Interact. 2019. PMID: 30553721 Review.
Interactions with the macrophages: An emerging targeted approach using novel drug delivery systems in respiratory diseases.
Mehta M, Deeksha, Sharma N, Vyas M, Khurana N, Maurya PK, Singh H, Andreoli de Jesus TP, Dureja H, Chellappan DK, Gupta G, Wadhwa R, Collet T, Hansbro PM, Dua K, Satija S. Mehta M, et al. Among authors: wadhwa r. Chem Biol Interact. 2019 May 1;304:10-19. doi: 10.1016/j.cbi.2019.02.021. Epub 2019 Mar 5. Chem Biol Interact. 2019. PMID: 30849336 Review.
Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases.
Mehta M, Deeksha, Tewari D, Gupta G, Awasthi R, Singh H, Pandey P, Chellappan DK, Wadhwa R, Collet T, Hansbro PM, Kumar SR, Thangavelu L, Negi P, Dua K, Satija S. Mehta M, et al. Among authors: wadhwa r. Chem Biol Interact. 2019 Aug 1;308:206-215. doi: 10.1016/j.cbi.2019.05.028. Epub 2019 May 25. Chem Biol Interact. 2019. PMID: 31136735 Free PMC article. Review.
Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases.
Chellappan DK, Sze Ning QL, Su Min SK, Bin SY, Chern PJ, Shi TP, Ee Mei SW, Yee TH, Qi OJ, Thangavelu L, Rajeshkumar S, Negi P, Chellian J, Wadhwa R, Gupta G, Collet T, Hansbro PM, Dua K. Chellappan DK, et al. Among authors: wadhwa r. Chem Biol Interact. 2019 Sep 1;310:108732. doi: 10.1016/j.cbi.2019.108732. Epub 2019 Jul 2. Chem Biol Interact. 2019. PMID: 31276660 Review.
Cellular mechanisms underlying steroid-resistant asthma.
Wadhwa R, Dua K, Adcock IM, Horvat JC, Kim RY, Hansbro PM. Wadhwa R, et al. Eur Respir Rev. 2019 Oct 21;28(153):190096. doi: 10.1183/16000617.0096-2019. Print 2019 Sep 30. Eur Respir Rev. 2019. PMID: 31636089 Free PMC article. Review.
Emerging Complexity and the Need for Advanced Drug Delivery in Targeting Candida Species.
Wadhwa R, Pandey P, Gupta G, Aggarwal T, Kumar N, Mehta M, Satija S, Gulati M, Madan JR, Dureja H, Balusamy SR, Perumalsamy H, Maurya PK, Collet T, Tambuwala MM, Hansbro PM, Chellappan DK, Dua K. Wadhwa R, et al. Curr Top Med Chem. 2019;19(28):2593-2609. doi: 10.2174/1568026619666191026105308. Curr Top Med Chem. 2019. PMID: 31746290 Review.
Immunological axis of berberine in managing inflammation underlying chronic respiratory inflammatory diseases.
Tew XN, Xin Lau NJ, Chellappan DK, Madheswaran T, Zeeshan F, Tambuwala MM, Aljabali AA, Balusamy SR, Perumalsamy H, Gupta G, Oliver BG, Hsu A, Wark P, Reddy K, Wadhwa R, Hansbro PM, Dua K. Tew XN, et al. Among authors: wadhwa r. Chem Biol Interact. 2020 Feb 1;317:108947. doi: 10.1016/j.cbi.2020.108947. Epub 2020 Jan 20. Chem Biol Interact. 2020. PMID: 31968208 Review.
526 results