Volcho KP - Search Results

1

The First Berberine-Based Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), an Important DNA Repair Enzyme.

Gladkova ED, Nechepurenko IV, Bredikhin RA, Chepanova AA, Zakharenko AL, Luzina OA, Ilina ES, Dyrkheeva NS, Mamontova EM, Anarbaev RO, Reynisson J, Volcho KP, Salakhutdinov NF, Lavrik OI. Gladkova ED, et al. Among authors: volcho kp. Int J Mol Sci. 2020 Sep 28;21(19):7162. doi: 10.3390/ijms21197162. Int J Mol Sci. 2020. PMID: 32998385 Free PMC article.

2

(4S,5R,6R)-para-mentha-1,8-dien-5,6-diol is a new highly effective anticonvulsant agent.

Tolstikova TG, Pavlova AV, Dolgikh MP, Il'ina IV, Ardashov OV, Volcho KP, Salakhutdinov NF, Tolstikov GA. Tolstikova TG, et al. Among authors: volcho kp. Dokl Biol Sci. 2009 Nov-Dec;429:494-6. doi: 10.1134/s0012496609060039. Dokl Biol Sci. 2009. PMID: 20170054 No abstract available.

3

A highly effective antiparkinsonian drug of a new structural type.

Tolstikova TG, Pavlova AV, Morozova YA, Ardashov OV, Il'ina IV, Volcho KP, Salakhutdinov NF, Tolstikov GA. Tolstikova TG, et al. Among authors: volcho kp. Dokl Biol Sci. 2010 Nov-Dec;435:398-9. doi: 10.1134/S0012496610060074. Epub 2011 Jan 9. Dokl Biol Sci. 2010. PMID: 21221892 No abstract available.

4

Highly potent activity of (1R,2R,6S)-3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol in animal models of Parkinson's disease.

Ardashov OV, Pavlova AV, Il'ina IV, Morozova EA, Korchagina DV, Karpova EV, Volcho KP, Tolstikova TG, Salakhutdinov NF. Ardashov OV, et al. Among authors: volcho kp. J Med Chem. 2011 Jun 9;54(11):3866-74. doi: 10.1021/jm2001579. Epub 2011 May 13. J Med Chem. 2011. PMID: 21534547

5

A new synthetic varacin analogue, 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine hydrochloride (TC-2153), decreased hereditary catalepsy and increased the BDNF gene expression in the hippocampus in mice.

Kulikov AV, Tikhonova MA, Kulikova EA, Volcho KP, Khomenko TM, Salakhutdinov NF, Popova NK. Kulikov AV, et al. Among authors: volcho kp. Psychopharmacology (Berl). 2012 Jun;221(3):469-78. doi: 10.1007/s00213-011-2594-8. Epub 2011 Nov 30. Psychopharmacology (Berl). 2012. PMID: 22127556

6

3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol: the importance of functional groups for antiparkinsonian activity.

Ardashov OV, Pavlova AV, Korchagina DV, Volcho KP, Tolstikova Ty, Salakhutdinov NF. Ardashov OV, et al. Among authors: volcho kp. Med Chem. 2013 Aug;9(5):731-9. doi: 10.2174/1573406411309050013. Med Chem. 2013. PMID: 23072553

7

Antiparkinsonian activity of some 9-N-, O-, S- and C-derivatives of 3-methyl-6-(prop-1-en-2-yl)cyclohex-3-ene-1,2-diol.

Ardashov OV, Pavlova AV, Korchagina DV, Volcho KP, Tolstikova TG, Salakhutdinov NF. Ardashov OV, et al. Among authors: volcho kp. Bioorg Med Chem. 2013 Mar 1;21(5):1082-7. doi: 10.1016/j.bmc.2013.01.003. Epub 2013 Jan 11. Bioorg Med Chem. 2013. PMID: 23375447

8

Effect of 2-aminoadamantane derivatives on behavior of mice in a modified light/dark test.

Avgustinovich DF, Fomina MK, Suslov EV, Tolstikova TG, Volcho KP, Salakhutdinov NF. Avgustinovich DF, et al. Among authors: volcho kp. Bull Exp Biol Med. 2014 Dec;158(2):213-8. doi: 10.1007/s10517-014-2725-4. Epub 2014 Nov 29. Bull Exp Biol Med. 2014. PMID: 25430650

9

The short way to chiral compounds with hexahydrofluoreno[9,1-bc]furan framework: synthesis and cytotoxic activity.

Kurbakova SY, Il'ina IV, Mikhalchenko OS, Pokrovsky MA, Korchagina DV, Volcho KP, Pokrovsky AG, Salakhutdinov NF. Kurbakova SY, et al. Among authors: volcho kp. Bioorg Med Chem. 2015 Apr 1;23(7):1472-80. doi: 10.1016/j.bmc.2015.02.013. Epub 2015 Feb 16. Bioorg Med Chem. 2015. PMID: 25737086

10

Synthesis and biological evaluation of novel tyrosyl-DNA phosphodiesterase 1 inhibitors with a benzopentathiepine moiety.

Zakharenko A, Khomenko T, Zhukova S, Koval O, Zakharova O, Anarbaev R, Lebedeva N, Korchagina D, Komarova N, Vasiliev V, Reynisson J, Volcho K, Salakhutdinov N, Lavrik O. Zakharenko A, et al. Bioorg Med Chem. 2015 May 1;23(9):2044-52. doi: 10.1016/j.bmc.2015.03.020. Epub 2015 Mar 12. Bioorg Med Chem. 2015. PMID: 25819333

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