Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1957 1
1959 1
1966 1
1968 1
1969 1
1974 3
1975 5
1976 4
1977 8
1978 8
1979 9
1980 11
1981 18
1982 16
1983 15
1984 37
1985 32
1986 19
1987 26
1988 33
1989 38
1990 36
1991 54
1992 43
1993 46
1994 51
1995 49
1996 45
1997 43
1998 34
1999 50
2000 42
2001 39
2002 52
2003 35
2004 42
2005 51
2006 39
2007 46
2008 42
2009 50
2010 56
2011 59
2012 77
2013 137
2014 242
2015 302
2016 349
2017 403
2018 459
2019 475
2020 521
2021 526
2022 460
2023 430
2024 196

Text availability

Article attribute

Article type

Publication date

Search Results

5,324 results

Results by year

Filters applied: . Clear all
Page 1
Showing results for vivo ro
Search for Vico RO instead (1 results)
In Vivo Receptor Occupancy in Rodents by LC-MS/MS.
Jesudason CD, DuBois S, Johnson M, Barth VN, Need AB. Jesudason CD, et al. 2017 Mar 9. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. 2017 Mar 9. In: Markossian S, Grossman A, Arkin M, Auld D, Austin C, Baell J, Brimacombe K, Chung TDY, Coussens NP, Dahlin JL, Devanarayan V, Foley TL, Glicksman M, Gorshkov K, Haas JV, Hall MD, Hoare S, Inglese J, Iversen PW, Lal-Nag M, Li Z, Manro JR, McGee J, McManus O, Pearson M, Riss T, Saradjian P, Sittampalam GS, Tarselli M, Trask OJ Jr, Weidner JR, Wildey MJ, Wilson K, Xia M, Xu X, editors. Assay Guidance Manual [Internet]. Bethesda (MD): Eli Lilly & Company and the National Center for Advancing Translational Sciences; 2004–. PMID: 28277627 Free Books & Documents. Review.
Receptor (or enzyme) Occupancy (RO) is a quantitative measure of what percentage of the total number of available target receptors is engaged by or bound to a particular ligand. ...Recent advances in the sensitivity of LC-MS/MS detectors have enabled determination of RO …
Receptor (or enzyme) Occupancy (RO) is a quantitative measure of what percentage of the total number of available target receptors is …
Cholesterol Biosynthesis Inhibitor RO 48-8071 Suppresses Growth of Epithelial Ovarian Cancer Cells in Vitro and In Vivo.
Liang Y, Nephew KP, Hyder SM. Liang Y, et al. J Cancer Sci Clin Ther. 2023;7(1):1-8. doi: 10.26502/jcsct.5079185. Epub 2023 Jan 9. J Cancer Sci Clin Ther. 2023. PMID: 38105923 Free PMC article.
Finally, xenograft studies were performed to assess the ability of RO 48-8071 to inhibit the growth of EOC cells in vivo. RESULTS: We found that short-term (24-48 h) administration of pharmacological doses of RO effectively reduced the viability of drug-resis …
Finally, xenograft studies were performed to assess the ability of RO 48-8071 to inhibit the growth of EOC cells in vivo. RESU …
Inhibitory Effects of Ginsenoside Ro on the Growth of B16F10 Melanoma via Its Metabolites.
Zheng SW, Xiao SY, Wang J, Hou W, Wang YP. Zheng SW, et al. Molecules. 2019 Aug 17;24(16):2985. doi: 10.3390/molecules24162985. Molecules. 2019. PMID: 31426477 Free PMC article.
We explored the anti-tumour activity of Ro in vivo in B16F10 tumour-bearing mice. The results revealed that Ro considerably suppressed tumour growth with no significant side effects on immune organs and body weight. ...The results suggest that the metabolites …
We explored the anti-tumour activity of Ro in vivo in B16F10 tumour-bearing mice. The results revealed that Ro consider …
Selective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513.
Pym LJ, Cook SM, Rosahl T, McKernan RM, Atack JR. Pym LJ, et al. Br J Pharmacol. 2005 Nov;146(6):817-25. doi: 10.1038/sj.bjp.0706392. Br J Pharmacol. 2005. PMID: 16184188 Free PMC article.
In the present study, an in vivo assay was developed using lorazepam to fully occupy DS receptors such that [3H]Ro 15-4513 was then only able to bind to DIS receptors. ...In these mice, and in the presence of lorazepam, there was an increase of in vivo [3H] …
In the present study, an in vivo assay was developed using lorazepam to fully occupy DS receptors such that [3H]Ro 15-4513 was …
Benzodiazepine receptor binding in vivo with [3H]-Ro 15-1788.
Goeders NE, Kuhar MJ. Goeders NE, et al. Life Sci. 1985 Jul 29;37(4):345-55. doi: 10.1016/0024-3205(85)90505-3. Life Sci. 1985. PMID: 2989650
In vivo benzodiazepine receptor binding has generally been studied by "ex vivo" techniques. In this investigation, we identify the conditions where [3H]-Ro 15-1788 labels benzodiazepine receptors by true "in vivo" binding, i.e. where workable specific …
In vivo benzodiazepine receptor binding has generally been studied by "ex vivo" techniques. In this investigation, we identify …
In vivo binding of (3H)Ro 15-1788 in mice: comparison with the in vivo binding of (3H)flunitrazepam.
Potier MC, Prado de Carvalho L, Dodd RH, Brown CL, Rossier J. Potier MC, et al. Life Sci. 1988;43(16):1287-96. doi: 10.1016/0024-3205(88)90583-8. Life Sci. 1988. PMID: 2845217
Benzodiazepine binding sites have generally been labelled with benzodiazepine agonists: (3H)flunitrazepam and (3H)diazepam in vivo. We studied the in vivo binding of the antagonist (3H)Ro 15-1788 in mice and compared it to the in vivo binding of (3H)fl …
Benzodiazepine binding sites have generally been labelled with benzodiazepine agonists: (3H)flunitrazepam and (3H)diazepam in vivo. W …
[Anti-SSA/Ro and anti-SSB/La antibodies. What's new?].
Meyer O. Meyer O. Ann Med Interne (Paris). 2002 Dec;153(8):520-9. Ann Med Interne (Paris). 2002. PMID: 12610426 Review. French.
These hYRNPs (h=human) can be found on the cytoplasmic membrane or in small blebs during apoptosis after various stimuli such as UVB, 17-beta-estradiol, viral infection, TNF alpha and other cellular apoptosis inducing molecules. At least two major different proteins are called SS …
These hYRNPs (h=human) can be found on the cytoplasmic membrane or in small blebs during apoptosis after various stimuli such as UVB, 17-bet …
In vivo evaluation of a dual-action antibacterial, Ro 23-9424, compared to cefotaxime and fleroxacin.
Beskid G, Siebelist J, McGarry CM, Cleeland R, Chan K, Keith DD. Beskid G, et al. Chemotherapy. 1990;36(2):109-16. doi: 10.1159/000238756. Chemotherapy. 1990. PMID: 2107064
Ro 23-9424 demonstrated significant activity against all strains tested in systemic infections, including those strains resistant in vivo to cefotaxime (Staphylococcus aureus 753, Serratia marcescens SM and Pseudomonas aeruginosa 8780) and fleroxacin (Streptococcus …
Ro 23-9424 demonstrated significant activity against all strains tested in systemic infections, including those strains resistant in …
In Vitro and In Vivo Characteristics of Olive Oil as Excipient for Topical Administration.
Rodríguez-Torrado M, Kara A, Torrado S, Romero A, Juberías A, Torrado JJ, Serrano DR. Rodríguez-Torrado M, et al. Pharmaceutics. 2022 Nov 26;14(12):2615. doi: 10.3390/pharmaceutics14122615. Pharmaceutics. 2022. PMID: 36559109 Free PMC article.
The in vivo performance of the oils in the skin of eight healthy volunteers was investigated with a dermoanalyser. ...An in vitro-in vivo correlation was therefore performed through multivariable analysis (MVA)....
The in vivo performance of the oils in the skin of eight healthy volunteers was investigated with a dermoanalyser. ...An in vitro-in …
Electropharmacology of Ro 22-9194, a new antiarrhythmic agent.
Kodama I, Maruyama K, Suzuki R, Honjo H, Toyama J. Kodama I, et al. Gen Pharmacol. 1996 Jul;27(5):755-60. doi: 10.1016/0306-3623(95)02094-2. Gen Pharmacol. 1996. PMID: 8842676 Review.
In dogs in vivo Ro 22-9194 (0.1-3 mg/kg, IV) caused a dose-dependent prolongation of atrioventricular conduction time with greater prolongation of His-ventricular (HV) than atrio-His (AH) intervals. Ro 22-9194 had a potent inhibitory action against various ty …
In dogs in vivo Ro 22-9194 (0.1-3 mg/kg, IV) caused a dose-dependent prolongation of atrioventricular conduction time with gre …
5,324 results