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Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Maseko SB, Brammerloo Y, Van Molle I, Sogues A, Martin C, Gorgulla C, Plant E, Olivet J, Blavier J, Ntombela T, Delvigne F, Arthanari H, El Hajj H, Bazarbachi A, Van Lint C, Salehi-Ashtiani K, Remaut H, Ballet S, Volkov AN, Twizere JC. Maseko SB, et al. Among authors: van molle i. Antiviral Res. 2023 Sep;217:105675. doi: 10.1016/j.antiviral.2023.105675. Epub 2023 Jul 21. Antiviral Res. 2023. PMID: 37481039
Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Rice HC, et al. Among authors: van molle i. Science. 2019 Jan 11;363(6423):eaao4827. doi: 10.1126/science.aao4827. Science. 2019. PMID: 30630900 Free PMC article.
Structure of the Prx6-subfamily 1-Cys peroxiredoxin from Sulfolobus islandicus.
Stroobants S, Van Molle I, Saidi Q, Jonckheere K, Maes D, Peeters E. Stroobants S, et al. Among authors: van molle i. Acta Crystallogr F Struct Biol Commun. 2019 Jun 1;75(Pt 6):428-434. doi: 10.1107/S2053230X19006472. Epub 2019 May 13. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31204689 Free PMC article.
Small-molecule inhibitors of the interaction between the E3 ligase VHL and HIF1α.
Buckley DL, Gustafson JL, Van Molle I, Roth AG, Tae HS, Gareiss PC, Jorgensen WL, Ciulli A, Crews CM. Buckley DL, et al. Among authors: van molle i. Angew Chem Int Ed Engl. 2012 Nov 12;51(46):11463-7. doi: 10.1002/anie.201206231. Epub 2012 Oct 12. Angew Chem Int Ed Engl. 2012. PMID: 23065727 Free PMC article.
30 results