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The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism.
Matalonga J, Glaria E, Bresque M, Escande C, Carbó JM, Kiefer K, Vicente R, León TE, Beceiro S, Pascual-García M, Serret J, Sanjurjo L, Morón-Ros S, Riera A, Paytubi S, Juarez A, Sotillo F, Lindbom L, Caelles C, Sarrias MR, Sancho J, Castrillo A, Chini EN, Valledor AF. Matalonga J, et al. Among authors: valledor af. Cell Rep. 2017 Jan 31;18(5):1241-1255. doi: 10.1016/j.celrep.2017.01.007. Cell Rep. 2017. PMID: 28147278 Free article.
Roles of CD38 in the Immune Response to Infection.
Glaría E, Valledor AF. Glaría E, et al. Among authors: valledor af. Cells. 2020 Jan 16;9(1):228. doi: 10.3390/cells9010228. Cells. 2020. PMID: 31963337 Free PMC article. Review.
Biological roles of liver X receptors in immune cells.
Pascual-García M, Valledor AF. Pascual-García M, et al. Among authors: valledor af. Arch Immunol Ther Exp (Warsz). 2012 Aug;60(4):235-49. doi: 10.1007/s00005-012-0179-9. Epub 2012 Jun 14. Arch Immunol Ther Exp (Warsz). 2012. PMID: 22696047 Free article. Review.
Reciprocal negative cross-talk between liver X receptors (LXRs) and STAT1: effects on IFN-γ-induced inflammatory responses and LXR-dependent gene expression.
Pascual-García M, Rué L, León T, Julve J, Carbó JM, Matalonga J, Auer H, Celada A, Escolà-Gil JC, Steffensen KR, Pérez-Navarro E, Valledor AF. Pascual-García M, et al. Among authors: valledor af. J Immunol. 2013 Jun 15;190(12):6520-32. doi: 10.4049/jimmunol.1201393. Epub 2013 May 17. J Immunol. 2013. PMID: 23686490
Liver X Receptor Nuclear Receptors Are Transcriptional Regulators of Dendritic Cell Chemotaxis.
Beceiro S, Pap A, Czimmerer Z, Sallam T, Guillén JA, Gallardo G, Hong C, A-Gonzalez N, Tabraue C, Diaz M, Lopez F, Matalonga J, Valledor AF, Dominguez P, Ardavin C, Delgado-Martin C, Partida-Sanchez S, Rodriguez-Fernandez JL, Nagy L, Tontonoz P, Castrillo A. Beceiro S, et al. Among authors: valledor af. Mol Cell Biol. 2018 Apr 30;38(10):e00534-17. doi: 10.1128/MCB.00534-17. Print 2018 May 15. Mol Cell Biol. 2018. PMID: 29507185 Free PMC article.
Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment.
Carbó JM, León TE, Font-Díaz J, De la Rosa JV, Castrillo A, Picard FR, Staudenraus D, Huber M, Cedó L, Escolà-Gil JC, Campos L, Bakiri L, Wagner EF, Caelles C, Stratmann T, Van Ginderachter JA, Valledor AF. Carbó JM, et al. Among authors: valledor af. Cancer Res. 2021 Feb 15;81(4):968-985. doi: 10.1158/0008-5472.CAN-19-3360. Epub 2020 Dec 23. Cancer Res. 2021. PMID: 33361391 Free article.
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