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Sexually dimorphic activation of innate antitumor immunity prevents adrenocortical carcinoma development.
Wilmouth JJ Jr, Olabe J, Garcia-Garcia D, Lucas C, Guiton R, Roucher-Boulez F, Dufour D, Damon-Soubeyrand C, Sahut-Barnola I, Pointud JC, Renaud Y, Levasseur A, Tauveron I, Lefrançois-Martinez AM, Martinez A, Val P. Wilmouth JJ Jr, et al. Among authors: val p. Sci Adv. 2022 Oct 14;8(41):eadd0422. doi: 10.1126/sciadv.add0422. Epub 2022 Oct 14. Sci Adv. 2022. PMID: 36240276 Free PMC article.
SF-1 (steroidogenic factor-1), C/EBPbeta (CCAAT/enhancer binding protein), and ubiquitous transcription factors NF1 (nuclear factor 1) and Sp1 (selective promoter factor 1) are required for regulation of the mouse aldose reductase-like gene (AKR1B7) expression in adrenocortical cells.
Aigueperse C, Val P, Pacot C, Darne C, Lalli E, Sassone-Corsi P, Veyssiere G, Jean C, Martinez A. Aigueperse C, et al. Among authors: val p. Mol Endocrinol. 2001 Jan;15(1):93-111. doi: 10.1210/mend.15.1.0577. Mol Endocrinol. 2001. PMID: 11145742
Decreased expression of cyclic adenosine monophosphate-regulated aldose reductase (AKR1B1) is associated with malignancy in human sporadic adrenocortical tumors.
Lefrançois-Martinez AM, Bertherat J, Val P, Tournaire C, Gallo-Payet N, Hyndman D, Veyssière G, Bertagna X, Jean C, Martinez A. Lefrançois-Martinez AM, et al. Among authors: val p. J Clin Endocrinol Metab. 2004 Jun;89(6):3010-9. doi: 10.1210/jc.2003-031830. J Clin Endocrinol Metab. 2004. PMID: 15181092
73 results