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Microglia-specific knock-down of Bmal1 improves memory and protects mice from high fat diet-induced obesity.
Wang XL, Kooijman S, Gao Y, Tzeplaeff L, Cosquer B, Milanova I, Wolff SEC, Korpel N, Champy MF, Petit-Demoulière B, Goncalves Da Cruz I, Sorg-Guss T, Rensen PCN, Cassel JC, Kalsbeek A, Boutillier AL, Yi CX. Wang XL, et al. Among authors: tzeplaeff l. Mol Psychiatry. 2021 Nov;26(11):6336-6349. doi: 10.1038/s41380-021-01169-z. Epub 2021 May 28. Mol Psychiatry. 2021. PMID: 34050326 Free PMC article.
Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator.
Chatterjee S, Cassel R, Schneider-Anthony A, Merienne K, Cosquer B, Tzeplaeff L, Halder Sinha S, Kumar M, Chaturbedy P, Eswaramoorthy M, Le Gras S, Keime C, Bousiges O, Dutar P, Petsophonsakul P, Rampon C, Cassel JC, Buée L, Blum D, Kundu TK, Boutillier AL. Chatterjee S, et al. Among authors: tzeplaeff l. EMBO Mol Med. 2018 Nov;10(11):e8587. doi: 10.15252/emmm.201708587. EMBO Mol Med. 2018. PMID: 30275019 Free PMC article.
The dark side of HDAC inhibition in ALS.
Boutillier AL, Tzeplaeff L, Dupuis L. Boutillier AL, et al. Among authors: tzeplaeff l. EBioMedicine. 2019 Mar;41:38-39. doi: 10.1016/j.ebiom.2019.02.039. Epub 2019 Feb 23. EBioMedicine. 2019. PMID: 30803935 Free PMC article. No abstract available.
Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
Scekic-Zahirovic J, Sanjuan-Ruiz I, Kan V, Megat S, De Rossi P, Dieterlé S, Cassel R, Jamet M, Kessler P, Wiesner D, Tzeplaeff L, Demais V, Sahadevan S, Hembach KM, Muller HP, Picchiarelli G, Mishra N, Antonucci S, Dirrig-Grosch S, Kassubek J, Rasche V, Ludolph A, Boutillier AL, Roselli F, Polymenidou M, Lagier-Tourenne C, Liebscher S, Dupuis L. Scekic-Zahirovic J, et al. Among authors: tzeplaeff l. Nat Commun. 2021 May 21;12(1):3028. doi: 10.1038/s41467-021-23187-9. Nat Commun. 2021. PMID: 34021132 Free PMC article.
Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription.
Paiva I, Cellai L, Meriaux C, Poncelet L, Nebie O, Saliou JM, Lacoste AS, Papegaey A, Drobecq H, Le Gras S, Schneider M, Malik EM, Müller CE, Faivre E, Carvalho K, Gomez-Murcia V, Vieau D, Thiroux B, Eddarkaoui S, Lebouvier T, Schueller E, Tzeplaeff L, Grgurina I, Seguin J, Stauber J, Lopes LV, Buée L, Buée-Scherrer V, Cunha RA, Ait-Belkacem R, Sergeant N, Annicotte JS, Boutillier AL, Blum D. Paiva I, et al. Among authors: tzeplaeff l. J Clin Invest. 2022 Jun 15;132(12):e149371. doi: 10.1172/JCI149371. J Clin Invest. 2022. PMID: 35536645 Free PMC article.