Turner NJ - Search Results

1

Structure-based discovery of a family of synthetic cyclophilin inhibitors showing a cyclosporin-A phenotype in Caenorhabditis elegans.

Yang Y, Moir E, Kontopidis G, Taylor P, Wear MA, Malone K, Dunsmore CJ, Page AP, Turner NJ, Walkinshaw MD. Yang Y, et al. Among authors: turner nj. Biochem Biophys Res Commun. 2007 Nov 30;363(4):1013-9. doi: 10.1016/j.bbrc.2007.09.079. Epub 2007 Oct 1. Biochem Biophys Res Commun. 2007. PMID: 17927958

2

Selective chemical intervention in the proteome of Caenorhabditis elegans.

Husi H, McAllister F, Angelopoulos N, Butler VJ, Bailey KR, Malone K, Mackay L, Taylor P, Page AP, Turner NJ, Barran PE, Walkinshaw M. Husi H, et al. Among authors: turner nj. J Proteome Res. 2010 Nov 5;9(11):6060-70. doi: 10.1021/pr100427c. Epub 2010 Sep 22. J Proteome Res. 2010. PMID: 20804218

3

Design and synthesis of conformationally constrained cyclophilin inhibitors showing a cyclosporin-A phenotype in C. elegans.

Dunsmore CJ, Malone KJ, Bailey KR, Wear MA, Florance H, Shirran S, Barran PE, Page AP, Walkinshaw MD, Turner NJ. Dunsmore CJ, et al. Among authors: turner nj. Chembiochem. 2011 Mar 21;12(5):802-10. doi: 10.1002/cbic.201000413. Epub 2011 Feb 17. Chembiochem. 2011. PMID: 21337480

4

A surface plasmon resonance-based assay for small molecule inhibitors of human cyclophilin A.

Wear MA, Patterson A, Malone K, Dunsmore C, Turner NJ, Walkinshaw MD. Wear MA, et al. Among authors: turner nj. Anal Biochem. 2005 Oct 15;345(2):214-26. doi: 10.1016/j.ab.2005.06.037. Anal Biochem. 2005. PMID: 16102717 Free PMC article.

5

A chemo-enzymatic route to enantiomerically pure cyclic tertiary amines.

Dunsmore CJ, Carr R, Fleming T, Turner NJ. Dunsmore CJ, et al. Among authors: turner nj. J Am Chem Soc. 2006 Feb 22;128(7):2224-5. doi: 10.1021/ja058536d. J Am Chem Soc. 2006. PMID: 16478171

6

Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis.

Nowicki MW, Tulloch LB, Worralll L, McNae IW, Hannaert V, Michels PA, Fothergill-Gilmore LA, Walkinshaw MD, Turner NJ. Nowicki MW, et al. Among authors: turner nj. Bioorg Med Chem. 2008 May 1;16(9):5050-61. doi: 10.1016/j.bmc.2008.03.045. Epub 2008 Mar 21. Bioorg Med Chem. 2008. PMID: 18387804

7

Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes.

Taylor P, Anderson V, Dowden J, Flitsch SL, Turner NJ, Loughran K, Walkinshaw MD. Taylor P, et al. Among authors: turner nj. J Biol Chem. 1999 Aug 27;274(35):24901-5. doi: 10.1074/jbc.274.35.24901. J Biol Chem. 1999. PMID: 10455164 Free article.

8

High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase.

Walker RG, Thomson G, Malone K, Nowicki MW, Brown E, Blake DG, Turner NJ, Walkinshaw MD, Grant KM, Mottram JC. Walker RG, et al. Among authors: turner nj. PLoS Negl Trop Dis. 2011 Apr 5;5(4):e1033. doi: 10.1371/journal.pntd.0001033. PLoS Negl Trop Dis. 2011. PMID: 21483720 Free PMC article.

9

Immobilised whole-cell recombinant monoamine oxidase biocatalysis.

Zajkoska P, Rosenberg M, Heath R, Malone KJ, Stloukal R, Turner NJ, Rebroš M. Zajkoska P, et al. Among authors: turner nj. Appl Microbiol Biotechnol. 2015 Feb;99(3):1229-36. doi: 10.1007/s00253-014-5983-1. Epub 2014 Aug 8. Appl Microbiol Biotechnol. 2015. PMID: 25104031

10

The crystal structure of P450-TT heme-domain provides the first structural insights into the versatile class VII P450s.

Tavanti M, Porter JL, Levy CW, Gómez Castellanos JR, Flitsch SL, Turner NJ. Tavanti M, et al. Among authors: turner nj. Biochem Biophys Res Commun. 2018 Jul 2;501(4):846-850. doi: 10.1016/j.bbrc.2018.05.014. Epub 2018 May 17. Biochem Biophys Res Commun. 2018. PMID: 29738765

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