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A Useful and Sustainable Role for N-of-1 Trials in the Healthcare Ecosystem.
Selker HP, Cohen T, D'Agostino RB, Dere WH, Ghaemi SN, Honig PK, Kaitin KI, Kaplan HC, Kravitz RL, Larholt K, McElwee NE, Oye KA, Palm ME, Perfetto E, Ramanathan C, Schmid CH, Seyfert-Margolis V, Trusheim M, Eichler HG. Selker HP, et al. Among authors: trusheim m. Clin Pharmacol Ther. 2022 Aug;112(2):224-232. doi: 10.1002/cpt.2425. Epub 2021 Oct 20. Clin Pharmacol Ther. 2022. PMID: 34551122 Free PMC article. Review.
Precision Reimbursement for Precision Medicine: Using Real-World Evidence to Evolve From Trial-and-Project to Track-and-Pay to Learn-and-Predict.
Eichler HG, Trusheim M, Schwarzer-Daum B, Larholt K, Zeitlinger M, Brunninger M, Sherman M, Strutton D, Hirsch G. Eichler HG, et al. Among authors: trusheim m. Clin Pharmacol Ther. 2022 Jan;111(1):52-62. doi: 10.1002/cpt.2471. Epub 2021 Nov 17. Clin Pharmacol Ther. 2022. PMID: 34716918 Free PMC article. Review.
The next frontier: Fostering innovation by improving health data access and utilization.
Oye KA, Jain G, Amador M, Arnaout R, Brown JS, Crown W, Ferguson J, Pezalla E, Rassen JA, Selker HP, Trusheim M, Hirsch G. Oye KA, et al. Among authors: trusheim m. Clin Pharmacol Ther. 2015 Nov;98(5):514-21. doi: 10.1002/cpt.191. Epub 2015 Sep 10. Clin Pharmacol Ther. 2015. PMID: 26234275 Free PMC article. Review. No abstract available.
"Threshold-crossing": A Useful Way to Establish the Counterfactual in Clinical Trials?
Eichler HG, Bloechl-Daum B, Bauer P, Bretz F, Brown J, Hampson LV, Honig P, Krams M, Leufkens H, Lim R, Lumpkin MM, Murphy MJ, Pignatti F, Posch M, Schneeweiss S, Trusheim M, Koenig F. Eichler HG, et al. Among authors: trusheim m. Clin Pharmacol Ther. 2016 Dec;100(6):699-712. doi: 10.1002/cpt.515. Epub 2016 Oct 19. Clin Pharmacol Ther. 2016. PMID: 27650716 Free PMC article.
From adaptive licensing to adaptive pathways: delivering a flexible life-span approach to bring new drugs to patients.
Eichler HG, Baird LG, Barker R, Bloechl-Daum B, Børlum-Kristensen F, Brown J, Chua R, Del Signore S, Dugan U, Ferguson J, Garner S, Goettsch W, Haigh J, Honig P, Hoos A, Huckle P, Kondo T, Le Cam Y, Leufkens H, Lim R, Longson C, Lumpkin M, Maraganore J, O'Rourke B, Oye K, Pezalla E, Pignatti F, Raine J, Rasi G, Salmonson T, Samaha D, Schneeweiss S, Siviero PD, Skinner M, Teagarden JR, Tominaga T, Trusheim MR, Tunis S, Unger TF, Vamvakas S, Hirsch G. Eichler HG, et al. Among authors: trusheim mr. Clin Pharmacol Ther. 2015 Mar;97(3):234-46. doi: 10.1002/cpt.59. Epub 2015 Feb 4. Clin Pharmacol Ther. 2015. PMID: 25669457 Free PMC article.
Corrigendum: Adaptive biomedical innovation: Evolving our global system to sustainably and safely bring new medicines to patients in need.
Hirsch G, Trusheim M, Cobbs E, Bala M, Garner S, Hartman D, Isaacs K, Lumpkin M, Lim R, Oye K, Pezalla E, Saltonstall P, Selker H. Hirsch G, et al. Among authors: trusheim m. Clin Pharmacol Ther. 2017 Apr;101(4):542. doi: 10.1002/cpt.643. Clin Pharmacol Ther. 2017. PMID: 28318021 Free PMC article. No abstract available.
54 results