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Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors.
Qvit N, Schechtman D, Pena DA, Berti DA, Soares CO, Miao Q, Liang LA, Baron LA, Teh-Poot C, Martínez-Vega P, Ramirez-Sierra MJ, Churchill E, Cunningham AD, Malkovskiy AV, Federspiel NA, Gozzo FC, Torrecilhas AC, Manso Alves MJ, Jardim A, Momar N, Dumonteil E, Mochly-Rosen D. Qvit N, et al. Among authors: torrecilhas ac. Int J Parasitol Drugs Drug Resist. 2016 Feb 12;6(1):74-84. doi: 10.1016/j.ijpddr.2016.02.003. eCollection 2016 Apr. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27054066 Free PMC article.
Novel structural CYP51 mutation in Trypanosoma cruzi associated with multidrug resistance to CYP51 inhibitors and reduced infectivity.
Franco CH, Warhurst DC, Bhattacharyya T, Au HYA, Le H, Giardini MA, Pascoalino BS, Torrecilhas AC, Romera LMD, Madeira RP, Schenkman S, Freitas-Junior LH, Chatelain E, Miles MA, Moraes CB. Franco CH, et al. Among authors: torrecilhas ac. Int J Parasitol Drugs Drug Resist. 2020 Aug;13:107-120. doi: 10.1016/j.ijpddr.2020.06.001. Epub 2020 Jun 13. Int J Parasitol Drugs Drug Resist. 2020. PMID: 32688218 Free PMC article.
In vitro and in vivo trypanocidal effects of the cyclopalladated compound 7a, a drug candidate for treatment of Chagas' disease.
Matsuo AL, Silva LS, Torrecilhas AC, Pascoalino BS, Ramos TC, Rodrigues EG, Schenkman S, Caires AC, Travassos LR. Matsuo AL, et al. Among authors: torrecilhas ac. Antimicrob Agents Chemother. 2010 Aug;54(8):3318-25. doi: 10.1128/AAC.00323-10. Epub 2010 May 17. Antimicrob Agents Chemother. 2010. PMID: 20479201 Free PMC article.
Pyrazinoates as antiparasitic agents against Trypanosoma cruzi.
Vasconcelos CI, Varela MT, Torrecilhas AC, Fernandes JPS. Vasconcelos CI, et al. Among authors: torrecilhas ac. Arch Pharm (Weinheim). 2018 Nov;351(11):e1800190. doi: 10.1002/ardp.201800190. Epub 2018 Oct 9. Arch Pharm (Weinheim). 2018. PMID: 30298951
74 results