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Examination of the Impact of Triazole Position within Linkers on Solubility and Lipophilicity of a CDK9 Degrader Series.
ACS Med Chem Lett. 2023 Jun 9;14(7):936-942. doi: 10.1021/acsmedchemlett.3c00082. eCollection 2023 Jul 13.
ACS Med Chem Lett. 2023.
PMID: 37465296
Bifunctional degraders of cyclin dependent kinase 9 (CDK9): Probing the relationship between linker length, properties, and selective protein degradation.
Tokarski RJ 2nd, Sharpe CM, Huntsman AC, Mize BK, Ayinde OR, Stahl EH, Lerma JR, Reed A, Carmichael B, Muthusamy N, Byrd JC, Fuchs JR.
Tokarski RJ 2nd, et al.
Eur J Med Chem. 2023 Jun 5;254:115342. doi: 10.1016/j.ejmech.2023.115342. Epub 2023 Apr 5.
Eur J Med Chem. 2023.
PMID: 37071962
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Evaluation of Novel Quorum Sensing Inhibitors Targeting Auto-Inducer 2 (AI-2) for the Control of Avian Pathogenic Escherichia coli Infections in Chickens.
Helmy YA, Kathayat D, Deblais L, Srivastava V, Closs G Jr, Tokarski RJ 2nd, Ayinde O, Fuchs JR, Rajashekara G.
Helmy YA, et al. Among authors: tokarski rj 2nd.
Microbiol Spectr. 2022 Jun 29;10(3):e0028622. doi: 10.1128/spectrum.00286-22. Epub 2022 May 18.
Microbiol Spectr. 2022.
PMID: 35583333
Free PMC article.
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Evaluation of synergy between host and pathogen-directed therapies against intracellular Leishmania donovani.
Zahid MSH, Johnson MM, Tokarski RJ 2nd, Satoskar AR, Fuchs JR, Bachelder EM, Ainslie KM.
Zahid MSH, et al. Among authors: tokarski rj 2nd.
Int J Parasitol Drugs Drug Resist. 2019 Aug;10:125-132. doi: 10.1016/j.ijpddr.2019.08.004. Epub 2019 Aug 21.
Int J Parasitol Drugs Drug Resist. 2019.
PMID: 31493763
Free PMC article.
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Total Synthesis of Scytonemide A Employing Weinreb AM Solid-Phase Resin.
Wilson TA, Tokarski RJ 2nd, Sullivan P, Demoret RM, Orjala J, Rakotondraibe LH, Fuchs JR.
Wilson TA, et al. Among authors: tokarski rj 2nd.
J Nat Prod. 2018 Mar 23;81(3):534-542. doi: 10.1021/acs.jnatprod.7b00912. Epub 2018 Feb 5.
J Nat Prod. 2018.
PMID: 29400964
Free PMC article.
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