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Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics.
Pérez-Vargas J, Shapira T, Olmstead AD, Villanueva I, Thompson CAH, Ennis S, Gao G, De Guzman J, Williams DE, Wang M, Chin A, Bautista-Sánchez D, Agafitei O, Levett P, Xie X, Nuzzo G, Freire VF, Quintana-Bulla JI, Bernardi DI, Gubiani JR, Suthiphasilp V, Raksat A, Meesakul P, Polbuppha I, Cheenpracha S, Jaidee W, Kanokmedhakul K, Yenjai C, Chaiyosang B, Teles HL, Manzo E, Fontana A, Leduc R, Boudreault PL, Berlinck RGS, Laphookhieo S, Kanokmedhakul S, Tietjen I, Cherkasov A, Krajden M, Nabi IR, Niikura M, Shi PY, Andersen RJ, Jean F. Pérez-Vargas J, et al. Among authors: tietjen i. Antiviral Res. 2023 Jan;209:105484. doi: 10.1016/j.antiviral.2022.105484. Epub 2022 Dec 8. Antiviral Res. 2023. PMID: 36503013 Free PMC article.
The Croton megalobotrys Müll Arg. traditional medicine in HIV/AIDS management: Documentation of patient use, in vitro activation of latent HIV-1 provirus, and isolation of active phorbol esters.
Tietjen I, Ngwenya BN, Fotso G, Williams DE, Simonambango S, Ngadjui BT, Andersen RJ, Brockman MA, Brumme ZL, Andrae-Marobela K. Tietjen I, et al. J Ethnopharmacol. 2018 Jan 30;211:267-277. doi: 10.1016/j.jep.2017.09.038. Epub 2017 Sep 29. J Ethnopharmacol. 2018. PMID: 28970153
Inhibition of NF-κB-dependent HIV-1 replication by the marine natural product bengamide A.
Tietjen I, Williams DE, Read S, Kuang XT, Mwimanzi P, Wilhelm E, Markle T, Kinloch NN, Naphen CN, Tenney K, Mesplède T, Wainberg MA, Crews P, Bell B, Andersen RJ, Brumme ZL, Brockman MA. Tietjen I, et al. Antiviral Res. 2018 Apr;152:94-103. doi: 10.1016/j.antiviral.2018.02.017. Epub 2018 Feb 22. Antiviral Res. 2018. PMID: 29476895
Put a cork in it: Plugging the M2 viral ion channel to sink influenza.
Jalily PH, Duncan MC, Fedida D, Wang J, Tietjen I. Jalily PH, et al. Among authors: tietjen i. Antiviral Res. 2020 Jun;178:104780. doi: 10.1016/j.antiviral.2020.104780. Epub 2020 Mar 27. Antiviral Res. 2020. PMID: 32229237 Free PMC article. Review.
51 results