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Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1.
Sellau J, Groneberg M, Fehling H, Thye T, Hoenow S, Marggraff C, Weskamm M, Hansen C, Stanelle-Bertram S, Kuehl S, Noll J, Wolf V, Metwally NG, Hagen SH, Dorn C, Wernecke J, Ittrich H, Tannich E, Jacobs T, Bruchhaus I, Altfeld M, Lotter H. Sellau J, et al. Among authors: thye t. Nat Commun. 2020 Jul 10;11(1):3459. doi: 10.1038/s41467-020-17260-y. Nat Commun. 2020. PMID: 32651360 Free PMC article.
Adhesion between P. falciparum infected erythrocytes and human endothelial receptors follows alternative binding dynamics under flow and febrile conditions.
Lubiana P, Bouws P, Roth LK, Dörpinghaus M, Rehn T, Brehmer J, Wichers JS, Bachmann A, Höhn K, Roeder T, Thye T, Gutsmann T, Burmester T, Bruchhaus I, Metwally NG. Lubiana P, et al. Among authors: thye t. Sci Rep. 2020 Mar 11;10(1):4548. doi: 10.1038/s41598-020-61388-2. Sci Rep. 2020. PMID: 32161335 Free PMC article.
Common virulence gene expression in adult first-time infected malaria patients and severe cases.
Wichers JS, Tonkin-Hill G, Thye T, Krumkamp R, Kreuels B, Strauss J, von Thien H, Scholz JA, Smedegaard Hansson H, Weisel Jensen R, Turner L, Lorenz FR, Schöllhorn A, Bruchhaus I, Tannich E, Fendel R, Otto TD, Lavstsen T, Gilberger TW, Duffy MF, Bachmann A. Wichers JS, et al. Among authors: thye t. Elife. 2021 Apr 28;10:e69040. doi: 10.7554/eLife.69040. Elife. 2021. PMID: 33908865 Free PMC article.
Genome-wide association study indicates two novel resistance loci for severe malaria.
Timmann C, Thye T, Vens M, Evans J, May J, Ehmen C, Sievertsen J, Muntau B, Ruge G, Loag W, Ansong D, Antwi S, Asafo-Adjei E, Nguah SB, Kwakye KO, Akoto AO, Sylverken J, Brendel M, Schuldt K, Loley C, Franke A, Meyer CG, Agbenyega T, Ziegler A, Horstmann RD. Timmann C, et al. Among authors: thye t. Nature. 2012 Sep 20;489(7416):443-6. doi: 10.1038/nature11334. Epub 2012 Aug 15. Nature. 2012. PMID: 22895189
Low Sensitivity of Real Time PCRs Targeting Retrotransposon Sequences for the Detection of Schistosoma japonicum Complex DNA in Human Serum.
Frickmann H, Loderstädt U, Nickel B, Poppert S, Odermatt P, Sayasone S, Van Esbroeck M, Micalessi I, Cnops L, Adisakwattana P, Leboulle G, Landt O, Thye T, Tannich E. Frickmann H, et al. Among authors: thye t. Pathogens. 2021 Aug 22;10(8):1067. doi: 10.3390/pathogens10081067. Pathogens. 2021. PMID: 34451531 Free PMC article.
Common variants at 11p13 are associated with susceptibility to tuberculosis.
Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewski F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff TH, Hill AV, Horstmann RD, Meyer CG. Thye T, et al. Nat Genet. 2012 Feb 5;44(3):257-9. doi: 10.1038/ng.1080. Nat Genet. 2012. PMID: 22306650 Free PMC article.
Transmission of Cryptosporidium Species Among Human and Animal Local Contact Networks in Sub-Saharan Africa: A Multicountry Study.
Krumkamp R, Aldrich C, Maiga-Ascofare O, Mbwana J, Rakotozandrindrainy N, Borrmann S, Caccio SM, Rakotozandrindrainy R, Adegnika AA, Lusingu JPA, Amuasi J, May J, Eibach D; CRYPTO Study Group. Krumkamp R, et al. Clin Infect Dis. 2021 Apr 26;72(8):1358-1366. doi: 10.1093/cid/ciaa223. Clin Infect Dis. 2021. PMID: 32150243 Free PMC article.
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nürnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, Nejentsev S. Curtis J, et al. Among authors: thye t. Nat Genet. 2015 May;47(5):523-527. doi: 10.1038/ng.3248. Epub 2015 Mar 16. Nat Genet. 2015. PMID: 25774636 Free PMC article.
55 results