Thomas D - Search Results

1

Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.

Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: thomas d, d andrea rj. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.

2

Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.

Guthridge MA, Stomski FC, Thomas D, Woodcock JM, Bagley CJ, Berndt MC, Lopez AF. Guthridge MA, et al. Among authors: thomas d. Stem Cells. 1998;16(5):301-13. doi: 10.1002/stem.160301. Stem Cells. 1998. PMID: 9766809 Review.

3

Identification of a 14-3-3 binding sequence in the common beta chain of the granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors that is serine-phosphorylated by GM-CSF.

Stomski FC, Dottore M, Winnall W, Guthridge MA, Woodcock J, Bagley CJ, Thomas DT, Andrews RK, Berndt MC, Lopez AF. Stomski FC, et al. Among authors: thomas dt. Blood. 1999 Sep 15;94(6):1933-42. Blood. 1999. PMID: 10477722 Free article.

4

Regulation of haematopoiesis by growth factors - emerging insights and therapies.

Thomas D, Vadas M, Lopez A. Thomas D, et al. Expert Opin Biol Ther. 2004 Jun;4(6):869-79. doi: 10.1517/14712598.4.6.869. Expert Opin Biol Ther. 2004. PMID: 15174969 Review.

5

14-3-3 protein signaling in development and growth factor responses.

Thomas D, Guthridge M, Woodcock J, Lopez A. Thomas D, et al. Curr Top Dev Biol. 2005;67:285-303. doi: 10.1016/S0070-2153(05)67009-3. Curr Top Dev Biol. 2005. PMID: 15949538 Review.

6

Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.

Guthridge MA, Powell JA, Barry EF, Stomski FC, McClure BJ, Ramshaw H, Felquer FA, Dottore M, Thomas DT, To B, Begley CG, Lopez AF. Guthridge MA, et al. EMBO J. 2006 Feb 8;25(3):479-89. doi: 10.1038/sj.emboj.7600948. Epub 2006 Jan 26. EMBO J. 2006. PMID: 16437163 Free PMC article.

7

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.

Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. Hercus TR, et al. Among authors: thomas d. Blood. 2009 Aug 13;114(7):1289-98. doi: 10.1182/blood-2008-12-164004. Epub 2009 May 12. Blood. 2009. PMID: 19436055 Free PMC article. Review.

8

Monoclonal antibody-mediated targeting of CD123, IL-3 receptor alpha chain, eliminates human acute myeloid leukemic stem cells.

Jin L, Lee EM, Ramshaw HS, Busfield SJ, Peoppl AG, Wilkinson L, Guthridge MA, Thomas D, Barry EF, Boyd A, Gearing DP, Vairo G, Lopez AF, Dick JE, Lock RB. Jin L, et al. Among authors: thomas d. Cell Stem Cell. 2009 Jul 2;5(1):31-42. doi: 10.1016/j.stem.2009.04.018. Cell Stem Cell. 2009. PMID: 19570512 Free article.

9

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML.

Powell JA, Thomas D, Barry EF, Kok CH, McClure BJ, Tsykin A, To LB, Brown A, Lewis ID, Herbert K, Goodall GJ, Speed TP, Asou N, Jacob B, Osato M, Haylock DN, Nilsson SK, D'Andrea RJ, Lopez AF, Guthridge MA. Powell JA, et al. Among authors: thomas d, d andrea rj. Blood. 2009 Nov 26;114(23):4859-70. doi: 10.1182/blood-2009-02-204818. Epub 2009 Oct 5. Blood. 2009. PMID: 19805619 Free article.

10

Molecular basis of cytokine receptor activation.

Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW. Lopez AF, et al. Among authors: thomas d, d andrea r. IUBMB Life. 2010 Jul;62(7):509-18. doi: 10.1002/iub.350. IUBMB Life. 2010. PMID: 20540154 Free article. Review.

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