Thiele NA - Search Results

1

²²⁵Ac-MACROPATATE: A Novel α-Particle Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors.

King AP, Gutsche NT, Raju N, Fayn S, Baidoo KE, Bell MM, Olkowski CS, Swenson RE, Lin FI, Sadowski SM, Adler SS, Thiele NA, Wilson JJ, Choyke PL, Escorcia FE. King AP, et al. Among authors: thiele na. J Nucl Med. 2023 Apr;64(4):549-554. doi: 10.2967/jnumed.122.264707. Epub 2022 Nov 17. J Nucl Med. 2023. PMID: 36396453 Free PMC article.

2

2-O-Acyl-3-O-(1-acyloxyalkyl) Prodrugs of 5,6-Isopropylidene-l-Ascorbic Acid and l-Ascorbic Acid: Antioxidant Activity and Ability to Permeate Silicone Membranes.

Thiele NA, McGowan J, Sloan KB. Thiele NA, et al. Pharmaceutics. 2016 Jul 18;8(3):22. doi: 10.3390/pharmaceutics8030022. Pharmaceutics. 2016. PMID: 27438850 Free PMC article.

3

Secondary carbamate linker can facilitate the sustained release of dopamine from brain-targeted prodrug.

Thiele NA, Kärkkäinen J, Sloan KB, Rautio J, Huttunen KM. Thiele NA, et al. Bioorg Med Chem Lett. 2018 Sep 15;28(17):2856-2860. doi: 10.1016/j.bmcl.2018.07.030. Epub 2018 Jul 18. Bioorg Med Chem Lett. 2018. PMID: 30055889

4

A Double Prodrug with Improved Membrane Permeability over the Parent Chelator HBED Provides Superior Cytoprotection against Hydrogen Peroxide.

Thiele NA, Sloan KB. Thiele NA, et al. ChemMedChem. 2016 Aug 5;11(15):1596-9. doi: 10.1002/cmdc.201600197. Epub 2016 Jul 21. ChemMedChem. 2016. PMID: 27440560

5

Novel double prodrugs of the iron chelator N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (HBED): Synthesis, characterization, and investigation of activation by chemical hydrolysis and oxidation.

Thiele NA, Abboud KA, Sloan KB. Thiele NA, et al. Eur J Med Chem. 2016 Aug 8;118:193-207. doi: 10.1016/j.ejmech.2016.04.037. Epub 2016 Apr 14. Eur J Med Chem. 2016. PMID: 27128183

6

An Eighteen-Membered Macrocyclic Ligand for Actinium-225 Targeted Alpha Therapy.

Thiele NA, Brown V, Kelly JM, Amor-Coarasa A, Jermilova U, MacMillan SN, Nikolopoulou A, Ponnala S, Ramogida CF, Robertson AKH, Rodríguez-Rodríguez C, Schaffer P, Williams C Jr, Babich JW, Radchenko V, Wilson JJ. Thiele NA, et al. Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14712-14717. doi: 10.1002/anie.201709532. Epub 2017 Oct 16. Angew Chem Int Ed Engl. 2017. PMID: 28963750

7

Actinium-225 for Targeted α Therapy: Coordination Chemistry and Current Chelation Approaches.

Thiele NA, Wilson JJ. Thiele NA, et al. Cancer Biother Radiopharm. 2018 Oct;33(8):336-348. doi: 10.1089/cbr.2018.2494. Epub 2018 Jun 11. Cancer Biother Radiopharm. 2018. PMID: 29889562 Free PMC article.

8

A Single Dose of ²²⁵Ac-RPS-074 Induces a Complete Tumor Response in an LNCaP Xenograft Model.

Kelly JM, Amor-Coarasa A, Ponnala S, Nikolopoulou A, Williams C Jr, Thiele NA, Schlyer D, Wilson JJ, DiMagno SG, Babich JW. Kelly JM, et al. Among authors: thiele na. J Nucl Med. 2019 May;60(5):649-655. doi: 10.2967/jnumed.118.219592. Epub 2018 Nov 9. J Nucl Med. 2019. PMID: 30413660 Free article.

9

Rapid Dissolution of BaSO₄ by Macropa, an 18-Membered Macrocycle with High Affinity for Ba².

Thiele NA, MacMillan SN, Wilson JJ. Thiele NA, et al. J Am Chem Soc. 2018 Dec 12;140(49):17071-17078. doi: 10.1021/jacs.8b08704. Epub 2018 Nov 28. J Am Chem Soc. 2018. PMID: 30485079 Free PMC article.

10

Implementing f-Block Metal Ions in Medicine: Tuning the Size Selectivity of Expanded Macrocycles.

Thiele NA, Woods JJ, Wilson JJ. Thiele NA, et al. Inorg Chem. 2019 Aug 19;58(16):10483-10500. doi: 10.1021/acs.inorgchem.9b01277. Epub 2019 Jun 27. Inorg Chem. 2019. PMID: 31246017

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