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Mutations in the nonstructural protein 3A confer resistance to the novel enterovirus replication inhibitor TTP-8307.
De Palma AM, Thibaut HJ, van der Linden L, Lanke K, Heggermont W, Ireland S, Andrews R, Arimilli M, Al-Tel TH, De Clercq E, van Kuppeveld F, Neyts J. De Palma AM, et al. Among authors: thibaut hj. Antimicrob Agents Chemother. 2009 May;53(5):1850-7. doi: 10.1128/AAC.00934-08. Epub 2009 Feb 23. Antimicrob Agents Chemother. 2009. PMID: 19237651 Free PMC article.
9-Arylpurines as a novel class of enterovirus inhibitors.
Aguado L, Thibaut HJ, Priego EM, Jimeno ML, Camarasa MJ, Neyts J, Pérez-Pérez MJ. Aguado L, et al. Among authors: thibaut hj. J Med Chem. 2010 Jan 14;53(1):316-24. doi: 10.1021/jm901240p. J Med Chem. 2010. PMID: 19924996
Efficient synthesis and anti-enteroviral activity of 9-arylpurines.
Aguado L, Canela MD, Thibaut HJ, Priego EM, Camarasa MJ, Leyssen P, Neyts J, Pérez-Pérez MJ. Aguado L, et al. Among authors: thibaut hj. Eur J Med Chem. 2012 Mar;49:279-88. doi: 10.1016/j.ejmech.2012.01.022. Epub 2012 Jan 17. Eur J Med Chem. 2012. PMID: 22305341
Selective serotonin reuptake inhibitor fluoxetine inhibits replication of human enteroviruses B and D by targeting viral protein 2C.
Ulferts R, van der Linden L, Thibaut HJ, Lanke KH, Leyssen P, Coutard B, De Palma AM, Canard B, Neyts J, van Kuppeveld FJ. Ulferts R, et al. Among authors: thibaut hj. Antimicrob Agents Chemother. 2013 Apr;57(4):1952-6. doi: 10.1128/AAC.02084-12. Epub 2013 Jan 18. Antimicrob Agents Chemother. 2013. PMID: 23335743 Free PMC article.
Molecular biology and inhibitors of hepatitis A virus.
Debing Y, Neyts J, Thibaut HJ. Debing Y, et al. Among authors: thibaut hj. Med Res Rev. 2014 Sep;34(5):895-917. doi: 10.1002/med.21292. Epub 2013 May 30. Med Res Rev. 2014. PMID: 23722879 Free PMC article. Review.
Binding of glutathione to enterovirus capsids is essential for virion morphogenesis.
Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Thibaut HJ, et al. PLoS Pathog. 2014 Apr 10;10(4):e1004039. doi: 10.1371/journal.ppat.1004039. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722756 Free PMC article.
55 results