Tellers DM - Search Results

1

Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions.

Zewge D, Butora G, Sherer EC, Tellers DM, Sidler DR, Gouker J, Copeland G, Jadhav V, Li Z, Armstrong J, Davies IW. Zewge D, et al. Among authors: tellers dm. Bioconjug Chem. 2018 Jun 20;29(6):1859-1865. doi: 10.1021/acs.bioconjchem.8b00298. Epub 2018 Jun 12. Bioconjug Chem. 2018. PMID: 29893553

2

High-throughput chemical modification of oligonucleotides for systematic structure-activity relationship evaluation.

Zewge D, Gosselin F, Kenski DM, Li J, Jadhav V, Yuan Y, Nerurkar SS, Tellers DM, Flanagan WM, Davies IW. Zewge D, et al. Among authors: tellers dm. Bioconjug Chem. 2014 Dec 17;25(12):2222-32. doi: 10.1021/bc500453q. Epub 2014 Nov 21. Bioconjug Chem. 2014. PMID: 25398098

3

Synthesis of vaniprevir (MK-7009): lactamization to prepare a 20-membered [corrected] macrocycle.

Song ZJ, Tellers DM, Journet M, Kuethe JT, Lieberman D, Humphrey G, Zhang F, Peng Z, Waters MS, Zewge D, Nolting A, Zhao D, Reamer RA, Dormer PG, Belyk KM, Davies IW, Devine PN, Tschaen DM. Song ZJ, et al. Among authors: tellers dm. J Org Chem. 2011 Oct 7;76(19):7804-15. doi: 10.1021/jo2011494. Epub 2011 Aug 31. J Org Chem. 2011. PMID: 21838271

4

Molecular umbrella conjugate for the ocular delivery of siRNA.

Janout V, Cline LL, Feuston BP, Klein L, O'Brien A, Tucker T, Yuan Y, O'Neill-Davis LA, Peiffer RL, Nerurkar SS, Jadhav V, Tellers DM, Regen SL. Janout V, et al. Among authors: tellers dm. Bioconjug Chem. 2014 Feb 19;25(2):197-201. doi: 10.1021/bc400506m. Epub 2014 Jan 23. Bioconjug Chem. 2014. PMID: 24433067 Free PMC article.

5

A [2 + 2] cycloaddition route to dimethylaminomethylene vinamidinium salts.

Davies IW, Tellers DM, Shultz CS, Fleitz FJ, Cai D, Sun Y. Davies IW, et al. Among authors: tellers dm. Org Lett. 2002 Aug 22;4(17):2969-72. doi: 10.1021/ol026383i. Org Lett. 2002. PMID: 12182601

6

Rapid HATU-mediated solution phase siRNA conjugation.

Aaronson JG, Klein LJ, Momose AA, O'Brien AM, Shaw AW, Tucker TJ, Yuan Y, Tellers DM. Aaronson JG, et al. Among authors: tellers dm. Bioconjug Chem. 2011 Aug 17;22(8):1723-8. doi: 10.1021/bc2001227. Epub 2011 Jul 11. Bioconjug Chem. 2011. PMID: 21744777

7

Highly diastereoselective heterogeneously catalyzed hydrogenation of enamines for the synthesis of chiral beta-amino acid derivatives.

Ikemoto N, Tellers DM, Dreher SD, Liu J, Huang A, Rivera NR, Njolito E, Hsiao Y, McWilliams JC, Williams JM, Armstrong JD 3rd, Sun Y, Mathre DJ, Grabowski EJ, Tillyer RD. Ikemoto N, et al. Among authors: tellers dm. J Am Chem Soc. 2004 Mar 17;126(10):3048-9. doi: 10.1021/ja038812t. J Am Chem Soc. 2004. PMID: 15012124

8

Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape.

Bartz R, Fan H, Zhang J, Innocent N, Cherrin C, Beck SC, Pei Y, Momose A, Jadhav V, Tellers DM, Meng F, Crocker LS, Sepp-Lorenzino L, Barnett SF. Bartz R, et al. Among authors: tellers dm. Biochem J. 2011 Apr 15;435(2):475-87. doi: 10.1042/BJ20101021. Biochem J. 2011. PMID: 21265735

9

Computational design and experimental characterization of peptides intended for pH-dependent membrane insertion and pore formation.

Zhang Y, Bartz R, Grigoryan G, Bryant M, Aaronson J, Beck S, Innocent N, Klein L, Procopio W, Tucker T, Jadhav V, Tellers DM, DeGrado WF. Zhang Y, et al. Among authors: tellers dm. ACS Chem Biol. 2015 Apr 17;10(4):1082-93. doi: 10.1021/cb500759p. Epub 2015 Jan 28. ACS Chem Biol. 2015. PMID: 25630033 Free PMC article.

10

Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Na_v1.7 for the Treatment of Pain.

Adams GL, Pall PS, Grauer SM, Zhou X, Ballard JE, Vavrek M, Kraus RL, Morissette P, Li N, Colarusso S, Bianchi E, Palani A, Klein R, John CT, Wang D, Tudor M, Nolting AF, Biba M, Nowak T, Makarov AA, Reibarkh M, Buevich AV, Zhong W, Regalado EL, Wang X, Gao Q, Shahripour A, Zhu Y, de Simone D, Frattarelli T, Pasquini NM, Magotti P, Iaccarino R, Li Y, Solly K, Lee KJ, Wang W, Chen F, Zeng H, Wang J, Regan H, Amin RP, Regan CP, Burgey CS, Henze DA, Sun C, Tellers DM. Adams GL, et al. Among authors: tellers dm. J Med Chem. 2022 Jan 13;65(1):485-496. doi: 10.1021/acs.jmedchem.1c01570. Epub 2021 Dec 21. J Med Chem. 2022. PMID: 34931831

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