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SARS-CoV-2 infection induces DNA damage, through CHK1 degradation and impaired 53BP1 recruitment, and cellular senescence.
Gioia U, Tavella S, Martínez-Orellana P, Cicio G, Colliva A, Ceccon M, Cabrini M, Henriques AC, Fumagalli V, Paldino A, Presot E, Rajasekharan S, Iacomino N, Pisati F, Matti V, Sepe S, Conte MI, Barozzi S, Lavagnino Z, Carletti T, Volpe MC, Cavalcante P, Iannacone M, Rampazzo C, Bussani R, Tripodo C, Zacchigna S, Marcello A, d'Adda di Fagagna F. Gioia U, et al. Among authors: tavella s. Nat Cell Biol. 2023 Apr;25(4):550-564. doi: 10.1038/s41556-023-01096-x. Epub 2023 Mar 9. Nat Cell Biol. 2023. PMID: 36894671 Free PMC article.
How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?
Willis CRG, Calvaruso M, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, Bottai D, Buchheim JI, Carnero-Diaz E, Castiglioni S, Cavalieri D, Ceccarelli G, Chouker A, Cialdai F, Ciofani G, Coppola G, Cusella G, Degl'Innocenti A, Desaphy JF, Frippiat JP, Gelinsky M, Genchi G, Grano M, Grimm D, Guignandon A, Herranz R, Hellweg C, Iorio CS, Karapantsios T, van Loon J, Lulli M, Maier J, Malda J, Mamaca E, Morbidelli L, Osterman A, Ovsianikov A, Pampaloni F, Pavezlorie E, Pereda-Campos V, Przybyla C, Rettberg P, Rizzo AM, Robson-Brown K, Rossi L, Russo G, Salvetti A, Risaliti C, Santucci D, Sperl M, Tabury K, Tavella S, Thielemann C, Willaert R, Monici M, Szewczyk NJ. Willis CRG, et al. Among authors: tavella s. NPJ Microgravity. 2024 May 1;10(1):50. doi: 10.1038/s41526-024-00395-3. NPJ Microgravity. 2024. PMID: 38693246 Free PMC article. Review.
How are cell and tissue structure and function influenced by gravity and what are the gravity perception mechanisms?
Davis T, Tabury K, Zhu S, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, Bottai D, Buchheim JI, Calvaruso M, Carnero-Diaz E, Castiglioni S, Cavalieri D, Ceccarelli G, Choukér A, Cialdai F, Ciofani G, Coppola G, Cusella G, Degl'Innocenti A, Desaphy JF, Frippiat JP, Gelinsky M, Genchi G, Grano M, Grimm D, Guignandon A, Hahn C, Hatton J, Herranz R, Hellweg CE, Iorio CS, Karapantsios T, van Loon JJWA, Lulli M, Maier J, Malda J, Mamaca E, Morbidelli L, van Ombergen A, Osterman A, Ovsianikov A, Pampaloni F, Pavezlorie E, Pereda-Campos V, Przybyla C, Puhl C, Rettberg P, Rizzo AM, Robson-Brown K, Rossi L, Russo G, Salvetti A, Santucci D, Sperl M, Tavella S, Thielemann C, Willaert R, Szewczyk N, Monici M. Davis T, et al. Among authors: tavella s. NPJ Microgravity. 2024 Feb 10;10(1):16. doi: 10.1038/s41526-024-00357-9. NPJ Microgravity. 2024. PMID: 38341423 Free PMC article.
How do gravity alterations affect animal and human systems at a cellular/tissue level?
Cialdai F, Brown AM, Baumann CW, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, Bottai D, Buchheim JI, Calvaruso M, Carnero-Diaz E, Castiglioni S, Cavalieri D, Ceccarelli G, Choukér A, Ciofani G, Coppola G, Cusella G, Degl'Innocenti A, Desaphy JF, Frippiat JP, Gelinsky M, Genchi G, Grano M, Grimm D, Guignandon A, Hahn C, Hatton J, Herranz R, Hellweg CE, Iorio CS, Karapantsios T, van Loon J, Lulli M, Maier J, Malda J, Mamaca E, Morbidelli L, van Ombergen A, Osterman A, Ovsianikov A, Pampaloni F, Pavezlorie E, Pereda-Campos V, Przybyla C, Puhl C, Rettberg P, Risaliti C, Rizzo AM, Robson-Brown K, Rossi L, Russo G, Salvetti A, Santucci D, Sperl M, Strollo F, Tabury K, Tavella S, Thielemann C, Willaert R, Szewczyk NJ, Monici M. Cialdai F, et al. Among authors: tavella s. NPJ Microgravity. 2023 Oct 21;9(1):84. doi: 10.1038/s41526-023-00330-y. NPJ Microgravity. 2023. PMID: 37865644 Free PMC article.
Prolonged exposure to simulated microgravity promotes stemness impairing morphological, metabolic and migratory profile of pancreatic cancer cells: a comprehensive proteomic, lipidomic and transcriptomic analysis.
Masini MA, Bonetto V, Manfredi M, Pastò A, Barberis E, Timo S, Vanella VV, Robotti E, Masetto F, Andreoli F, Fiore A, Tavella S, Sica A, Donadelli M, Marengo E. Masini MA, et al. Among authors: tavella s. Cell Mol Life Sci. 2022 Apr 7;79(5):226. doi: 10.1007/s00018-022-04243-z. Cell Mol Life Sci. 2022. PMID: 35391557 Free PMC article.
63 results