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Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation.
Zhu G, Xie J, Kong W, Xie J, Li Y, Du L, Zheng Q, Sun L, Guan M, Li H, Zhu T, He H, Liu Z, Xia X, Kan C, Tao Y, Shen HC, Li D, Wang S, Yu Y, Yu ZH, Zhang ZY, Liu C, Zhu J. Zhu G, et al. Among authors: tao y. Cell. 2020 Oct 15;183(2):490-502.e18. doi: 10.1016/j.cell.2020.09.002. Epub 2020 Sep 30. Cell. 2020. PMID: 33002410 Free PMC article.
A novel partially open state of SHP2 points to a "multiple gear" regulation mechanism.
Tao Y, Xie J, Zhong Q, Wang Y, Zhang S, Luo F, Wen F, Xie J, Zhao J, Sun X, Long H, Ma J, Zhang Q, Long J, Fang X, Lu Y, Li D, Li M, Zhu J, Sun B, Li G, Diao J, Liu C. Tao Y, et al. J Biol Chem. 2021 Jan-Jun;296:100538. doi: 10.1016/j.jbc.2021.100538. Epub 2021 Mar 12. J Biol Chem. 2021. PMID: 33722610 Free PMC article.
Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.
Zhang S, Liu YQ, Jia C, Lim YJ, Feng G, Xu E, Long H, Kimura Y, Tao Y, Zhao C, Wang C, Liu Z, Hu JJ, Ma MR, Liu Z, Jiang L, Li D, Wang R, Dawson VL, Dawson TM, Li YM, Mao X, Liu C. Zhang S, et al. Among authors: tao y. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2011196118. doi: 10.1073/pnas.2011196118. Proc Natl Acad Sci U S A. 2021. PMID: 34172566 Free PMC article.
8,404 results