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Advances in the study of drug metabolism - symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX).
Russell LE, Schleiff MA, Gonzalez E, Bart AG, Broccatelli F, Hartman JH, Humphreys WG, Lauschke VM, Martin I, Nwabufo C, Prasad B, Scott EE, Segall M, Takahashi R, Taub ME, Sodhi JK. Russell LE, et al. Among authors: takahashi r. Drug Metab Rev. 2020 Aug;52(3):395-407. doi: 10.1080/03602532.2020.1765793. Epub 2020 May 26. Drug Metab Rev. 2020. PMID: 32456484 Free PMC article. Review.
Bioactivation and reactivity research advances - 2022 year in review‡.
Wang S, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wei C, Khojasteh SC. Wang S, et al. Drug Metab Rev. 2023 Nov;55(4):267-300. doi: 10.1080/03602532.2023.2244193. Epub 2023 Aug 22. Drug Metab Rev. 2023. PMID: 37608698 Review.
Biotransformation research advances - 2022 year in review.
Khojasteh SC, Argikar UA, Cheruzel L, Cho S, Crouch RD, Dhaware D, Heck CJS, Johnson KM, Kalgutkar AS, King L, Liu J, Ma B, Maw H, Miller GP, Seneviratne HK, Takahashi RH, Wang S, Wei C, Jackson KD. Khojasteh SC, et al. Drug Metab Rev. 2023 Nov;55(4):301-342. doi: 10.1080/03602532.2023.2262161. Epub 2023 Oct 28. Drug Metab Rev. 2023. PMID: 37737116 Review.
Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening.
Yue Q, Chen YH, Mulder T, Deese A, Takahashi R, Rudewicz PJ, Reynolds M, Solon E, Hop CE, Wong H, Khojasteh SC. Yue Q, et al. Among authors: takahashi r. Drug Metab Dispos. 2011 Jun;39(6):952-65. doi: 10.1124/dmd.110.037374. Epub 2011 Mar 1. Drug Metab Dispos. 2011. PMID: 21363998
Investigations into the mechanisms of pyridine ring cleavage in vismodegib.
Khojasteh SC, Yue Q, Ma S, Castanedo G, Chen JZ, Lyssikatos J, Mulder T, Takahashi R, Ly J, Messick K, Jia W, Liu L, Hop CE, Wong H. Khojasteh SC, et al. Among authors: takahashi r. Drug Metab Dispos. 2014 Mar;42(3):343-51. doi: 10.1124/dmd.113.055715. Epub 2014 Jan 3. Drug Metab Dispos. 2014. PMID: 24389420
3,005 results