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Pharmacological Inhibition of Succinyl Coenzyme A:3-Ketoacid Coenzyme A Transferase Alleviates the Progression of Diabetic Cardiomyopathy.
Greenwell AA, Tabatabaei Dakhili SA, Wagg CS, Saed CT, Chan JSF, Yang K, Mangra-Bala IA, Stenlund MJ, Eaton F, Gopal K, Dyck JRB, Lopaschuk GD, Ussher JR. Greenwell AA, et al. Among authors: tabatabaei dakhili sa. J Am Heart Assoc. 2024 Apr 2;13(7):e032697. doi: 10.1161/JAHA.123.032697. Epub 2024 Mar 27. J Am Heart Assoc. 2024. PMID: 38533954 Free article. No abstract available.
Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease.
Chen J, Farraj RA, Limonta D, Tabatabaei Dakhili SA, Kerek EM, Bhattacharya A, Reformat FM, Mabrouk OM, Brigant B, Pfeifer TA, McDermott MT, Ussher JR, Hobman TC, Glover JNM, Hubbard BP. Chen J, et al. Among authors: tabatabaei dakhili sa. J Biol Chem. 2023 Nov;299(11):105341. doi: 10.1016/j.jbc.2023.105341. Epub 2023 Oct 11. J Biol Chem. 2023. PMID: 37832873 Free PMC article.
Ketone ester administration improves glycemia in obese mice.
Tabatabaei Dakhili SA, Yang K, Locatelli CAA, Saed CT, Greenwell AA, Chan JSF, Chahade JJ, Scharff J, Al-Imarah S, Eaton F, Crawford PA, Gopal K, Mulvihill EE, Ussher JR. Tabatabaei Dakhili SA, et al. Am J Physiol Cell Physiol. 2023 Sep 1;325(3):C750-C757. doi: 10.1152/ajpcell.00300.2023. Epub 2023 Aug 14. Am J Physiol Cell Physiol. 2023. PMID: 37575059
Defective muscle ketone body oxidation disrupts BCAA catabolism by altering mitochondrial branched-chain aminotransferase.
Mechchate H, Abdualkader AM, Bernacchi JB, Gopal K, Tabatabaei Dakhili SA, Yang K, Greenwell AA, Kong X, Crawford PA, Al Batran R. Mechchate H, et al. Among authors: tabatabaei dakhili sa. Am J Physiol Endocrinol Metab. 2023 May 1;324(5):E425-E436. doi: 10.1152/ajpendo.00206.2022. Epub 2023 Mar 29. Am J Physiol Endocrinol Metab. 2023. PMID: 36989424 Free article.
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.
Gopal K, Karwi QG, Tabatabaei Dakhili SA, Wagg CS, Zhang L, Sun Q, Saed CT, Panidarapu S, Perfetti R, Ramasamy R, Ussher JR, Lopaschuk GD. Gopal K, et al. Among authors: tabatabaei dakhili sa. Cardiovasc Diabetol. 2023 Mar 28;22(1):73. doi: 10.1186/s12933-023-01811-w. Cardiovasc Diabetol. 2023. PMID: 36978133 Free PMC article.
The Antipsychotic Dopamine 2 Receptor Antagonist Diphenylbutylpiperidines Improve Glycemia in Experimental Obesity by Inhibiting Succinyl-CoA:3-Ketoacid CoA Transferase.
Tabatabaei Dakhili SA, Greenwell AA, Yang K, Abou Farraj R, Saed CT, Gopal K, Chan JSF, Chahade JJ, Eaton F, Lee C, Velázquez-Martínez CA, Crawford PA, Glover JNM, Al Batran R, Ussher JR. Tabatabaei Dakhili SA, et al. Diabetes. 2023 Jan 1;72(1):126-134. doi: 10.2337/db22-0221. Diabetes. 2023. PMID: 36256885
Stimulating myocardial pyruvate dehydrogenase activity fails to alleviate cardiac abnormalities in a mouse model of human Barth syndrome.
Greenwell AA, Tabatabaei Dakhili SA, Gopal K, Saed CT, Chan JSF, Kazungu Mugabo N, Zhabyeyev P, Eaton F, Kruger J, Oudit GY, Ussher JR. Greenwell AA, et al. Among authors: tabatabaei dakhili sa. Front Cardiovasc Med. 2022 Sep 23;9:997352. doi: 10.3389/fcvm.2022.997352. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 36211560 Free PMC article.
24 results