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Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense.
Moschos SA, Frick M, Taylor B, Turnpenny P, Graves H, Spink KG, Brady K, Lamb D, Collins D, Rockel TD, Weber M, Lazari O, Perez-Tosar L, Fancy SA, Lapthorn C, Green MX, Evans S, Selby M, Jones G, Jones L, Kearney S, Mechiche H, Gikunju D, Subramanian R, Uhlmann E, Jurk M, Vollmer J, Ciaramella G, Yeadon M. Moschos SA, et al. Among authors: subramanian r. Mol Ther. 2011 Dec;19(12):2163-8. doi: 10.1038/mt.2011.206. Epub 2011 Oct 4. Mol Ther. 2011. PMID: 21971426 Free PMC article.
SERPINA1 mRNA as a Treatment for Alpha-1 Antitrypsin Deficiency.
Connolly B, Isaacs C, Cheng L, Asrani KH, Subramanian RR. Connolly B, et al. Among authors: subramanian rr. J Nucleic Acids. 2018 Jun 13;2018:8247935. doi: 10.1155/2018/8247935. eCollection 2018. J Nucleic Acids. 2018. PMID: 30009048 Free PMC article.
Leveraging Rational Protein Engineering to Improve mRNA Therapeutics.
Farelli JD, Asrani KH, Isaacs C, deBear JS, Stahley MR, Shah A, Lasaro MA, Cheng CJ, Subramanian RR. Farelli JD, et al. Among authors: subramanian rr. Nucleic Acid Ther. 2018 Apr;28(2):74-85. doi: 10.1089/nat.2017.0697. Epub 2018 Feb 13. Nucleic Acid Ther. 2018. PMID: 29437538
Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice.
Desjardins CA, Yao M, Hall J, O'Donnell E, Venkatesan R, Spring S, Wen A, Hsia N, Shen P, Russo R, Lan B, Picariello T, Tang K, Weeden T, Zanotti S, Subramanian R, Ibraghimov-Beskrovnaya O. Desjardins CA, et al. Among authors: subramanian r. Nucleic Acids Res. 2022 Nov 11;50(20):11401-11414. doi: 10.1093/nar/gkac641. Nucleic Acids Res. 2022. PMID: 35944903 Free PMC article.
718 results