Steigele S - Search Results

1

Considerations for improved performance of competition association assays analysed with the Motulsky-Mahan's "kinetics of competitive binding" model.

Georgi V, Dubrovskiy A, Steigele S, Fernández-Montalván AE. Georgi V, et al. Among authors: steigele s. Br J Pharmacol. 2019 Dec;176(24):4731-4744. doi: 10.1111/bph.14841. Epub 2019 Dec 26. Br J Pharmacol. 2019. PMID: 31444916 Free PMC article.

2

Know When You Don't Know: A Robust Deep Learning Approach in the Presence of Unknown Phenotypes.

Dürr O, Murina E, Siegismund D, Tolkachev V, Steigele S, Sick B. Dürr O, et al. Among authors: steigele s. Assay Drug Dev Technol. 2018 Aug/Sep;16(6):343-349. doi: 10.1089/adt.2018.859. Assay Drug Dev Technol. 2018. PMID: 30148665

3

Deep Learning-Based HCS Image Analysis for the Enterprise.

Steigele S, Siegismund D, Fassler M, Kustec M, Kappler B, Hasaka T, Yee A, Brodte A, Heyse S. Steigele S, et al. SLAS Discov. 2020 Aug;25(7):812-821. doi: 10.1177/2472555220918837. Epub 2020 May 20. SLAS Discov. 2020. PMID: 32432952 Free PMC article.

4

An efficient and scalable data analysis solution for automated electrophysiology platforms.

Li T, Ginkel M, Yee AX, Foster L, Chen J, Heyse S, Steigele S. Li T, et al. Among authors: steigele s. SLAS Discov. 2022 Jun;27(4):278-285. doi: 10.1016/j.slasd.2021.11.001. Epub 2021 Dec 4. SLAS Discov. 2022. PMID: 35058183 Free article.

5

High-throughput mechanistic screening of non-equilibrium inhibitors by a fully automated data analysis pipeline in early drug-discovery.

Srinivasan B, Flórez Weidinger JD, Zhai X, Lemercier G, Ikeda T, Brewer M, Zhang B, Heyse S, Wingfield J, Steigele S. Srinivasan B, et al. Among authors: steigele s. SLAS Discov. 2022 Dec;27(8):460-470. doi: 10.1016/j.slasd.2022.09.003. Epub 2022 Sep 23. SLAS Discov. 2022. PMID: 36156314 Free article.

6

Developing Deep Learning Applications for Life Science and Pharma Industry.

Siegismund D, Tolkachev V, Heyse S, Sick B, Duerr O, Steigele S. Siegismund D, et al. Among authors: steigele s. Drug Res (Stuttg). 2018 Jun;68(6):305-310. doi: 10.1055/s-0043-124761. Epub 2018 Jan 16. Drug Res (Stuttg). 2018. PMID: 29341027

7

Benchmarking feature selection methods for compressing image information in high-content screening.

Siegismund D, Fassler M, Heyse S, Steigele S. Siegismund D, et al. Among authors: steigele s. SLAS Technol. 2022 Feb;27(1):85-93. doi: 10.1016/j.slast.2021.10.015. Epub 2021 Oct 25. SLAS Technol. 2022. PMID: 35058213 Free article.

8

Unified Software Solution for Efficient SPR Data Analysis in Drug Research.

Dahl G, Steigele S, Hillertz P, Tigerström A, Egnéus A, Mehrle A, Ginkel M, Edfeldt F, Holdgate G, O'Connell N, Kappler B, Brodte A, Rawlins PB, Davies G, Westberg EL, Folmer RH, Heyse S. Dahl G, et al. Among authors: steigele s. SLAS Discov. 2017 Feb;22(2):203-209. doi: 10.1177/1087057116675316. Epub 2016 Oct 28. SLAS Discov. 2017. PMID: 27789754 Free PMC article.

9

Genomic organization of eukaryotic tRNAs.

Bermudez-Santana C, Attolini CS, Kirsten T, Engelhardt J, Prohaska SJ, Steigele S, Stadler PF. Bermudez-Santana C, et al. Among authors: steigele s. BMC Genomics. 2010 Apr 28;11:270. doi: 10.1186/1471-2164-11-270. BMC Genomics. 2010. PMID: 20426822 Free PMC article.

10

Noncoding RNA of glutamine synthetase I modulates antibiotic production in Streptomyces coelicolor A3(2).

D'Alia D, Nieselt K, Steigele S, Müller J, Verburg I, Takano E. D'Alia D, et al. Among authors: steigele s. J Bacteriol. 2010 Feb;192(4):1160-4. doi: 10.1128/JB.01374-09. Epub 2009 Dec 4. J Bacteriol. 2010. PMID: 19966003 Free PMC article.

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