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Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists.
Ho KK, Auld DS, Bohnstedt AC, Conti P, Dokter W, Erickson S, Feng D, Inglese J, Kingsbury C, Kultgen SG, Liu RQ, Masterson CM, Ohlmeyer M, Rong Y, Rooseboom M, Roughton A, Samama P, Smit MJ, Son E, van der Louw J, Vogel G, Webb M, Wijkmans J, You M. Ho KK, et al. Among authors: smit mj. Bioorg Med Chem Lett. 2006 May 15;16(10):2724-8. doi: 10.1016/j.bmcl.2006.02.028. Epub 2006 Mar 15. Bioorg Med Chem Lett. 2006. PMID: 16540318
Artemether-lumefantrine with or without single-dose primaquine and sulfadoxine-pyrimethamine plus amodiaquine with or without single-dose tafenoquine to reduce Plasmodium falciparum transmission: a phase 2, single-blind, randomised clinical trial in Ouelessebougou, Mali.
Mahamar A, Smit MJ, Sanogo K, Sinaba Y, Niambele SM, Sacko A, Dicko OM, Diallo M, Maguiraga SO, Sankaré Y, Keita S, Samake S, Dembele A, Lanke K, Ter Heine R, Bradley J, Dicko Y, Traore SF, Drakeley C, Dicko A, Bousema T, Stone W. Mahamar A, et al. Among authors: smit mj. Lancet Microbe. 2024 May 2:S2666-5247(24)00023-5. doi: 10.1016/S2666-5247(24)00023-5. Online ahead of print. Lancet Microbe. 2024. PMID: 38705163 Free article.
A Pfs48/45-based vaccine to block Plasmodium falciparum transmission: phase 1, open-label, clinical trial.
Alkema M, Smit MJ, Marin-Mogollon C, Totté K, Teelen K, van Gemert GJ, van de Vegte-Bolmer M, Mordmüller BG, Reimer JM, Lövgren-Bengtsson KL, Sauerwein RW, Bousema T, Plieskatt J, Theisen M, Jore MM, McCall MBB. Alkema M, et al. Among authors: smit mj. BMC Med. 2024 Apr 23;22(1):170. doi: 10.1186/s12916-024-03379-y. BMC Med. 2024. PMID: 38649867 Free PMC article. Clinical Trial.
Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3.
Zarca AM, Adlere I, Viciano CP, Arimont-Segura M, Meyrath M, Simon IA, Bebelman JP, Laan D, Custers HGJ, Janssen E, Versteegh KL, Buzink MCML, Nesheva DN, Bosma R, de Esch IJP, Vischer HF, Wijtmans M, Szpakowska M, Chevigné A, Hoffmann C, de Graaf C, Zarzycka BA, Windhorst AD, Smit MJ, Leurs R. Zarca AM, et al. Among authors: smit mj. Mol Pharmacol. 2024 Mar 14;105(4):301-312. doi: 10.1124/molpharm.123.000835. Mol Pharmacol. 2024. PMID: 38346795
263 results