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Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.
Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt M, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. Stahnke S, et al. Among authors: sixt m. Curr Biol. 2021 May 24;31(10):2051-2064.e8. doi: 10.1016/j.cub.2021.02.043. Epub 2021 Mar 11. Curr Biol. 2021. PMID: 33711252 Free article.
Editorial overview: Cell adhesion and migration.
Sixt M, Raz E. Sixt M, et al. Curr Opin Cell Biol. 2015 Oct;36:iv-vi. doi: 10.1016/j.ceb.2015.09.004. Epub 2015 Oct 11. Curr Opin Cell Biol. 2015. PMID: 26459173 No abstract available.
Focal Adhesion-Independent Cell Migration.
Paluch EK, Aspalter IM, Sixt M. Paluch EK, et al. Among authors: sixt m. Annu Rev Cell Dev Biol. 2016 Oct 6;32:469-490. doi: 10.1146/annurev-cellbio-111315-125341. Epub 2016 Aug 4. Annu Rev Cell Dev Biol. 2016. PMID: 27501447 Review.
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.
Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M. Leithner A, et al. Among authors: sixt m. Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24. Nat Cell Biol. 2016. PMID: 27775702
Cell Migration: Making the Waves.
Müller J, Sixt M. Müller J, et al. Among authors: sixt m. Curr Biol. 2017 Jan 9;27(1):R24-R25. doi: 10.1016/j.cub.2016.11.035. Curr Biol. 2017. PMID: 28073017 Free article.
FMNL formins boost lamellipodial force generation.
Kage F, Winterhoff M, Dimchev V, Mueller J, Thalheim T, Freise A, Brühmann S, Kollasser J, Block J, Dimchev G, Geyer M, Schnittler HJ, Brakebusch C, Stradal TE, Carlier MF, Sixt M, Käs J, Faix J, Rottner K. Kage F, et al. Among authors: sixt m. Nat Commun. 2017 Mar 22;8:14832. doi: 10.1038/ncomms14832. Nat Commun. 2017. PMID: 28327544 Free PMC article.
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity.
Salzer E, Zoghi S, Kiss MG, Kage F, Rashkova C, Stahnke S, Haimel M, Platzer R, Caldera M, Ardy RC, Hoeger B, Block J, Medgyesi D, Sin C, Shahkarami S, Kain R, Ziaee V, Hammerl P, Bock C, Menche J, Dupré L, Huppa JB, Sixt M, Lomakin A, Rottner K, Binder CJ, Stradal TEB, Rezaei N, Boztug K. Salzer E, et al. Among authors: sixt m. Sci Immunol. 2020 Jul 10;5(49):eabc3979. doi: 10.1126/sciimmunol.abc3979. Sci Immunol. 2020. PMID: 32646852 Free PMC article.
134 results