Singleton DG - Search Results

1

AT-CuAAC Synthesis of Mechanically Interlocked Oligonucleotides.

Acevedo-Jake A, Ball AT, Galli M, Kukwikila M, Denis M, Singleton DG, Tavassoli A, Goldup SM. Acevedo-Jake A, et al. Among authors: singleton dg. J Am Chem Soc. 2020 Apr 1;142(13):5985-5990. doi: 10.1021/jacs.0c01670. Epub 2020 Mar 20. J Am Chem Soc. 2020. PMID: 32155338 Free PMC article.

2

Development of Gene-Targeted Polypyridyl Triplex-Forming Oligonucleotide Hybrids.

Zuin Fantoni N, McGorman B, Molphy Z, Singleton D, Walsh S, El-Sagheer AH, McKee V, Brown T, Kellett A. Zuin Fantoni N, et al. Chembiochem. 2020 Dec 11;21(24):3563-3574. doi: 10.1002/cbic.202000408. Epub 2020 Sep 24. Chembiochem. 2020. PMID: 32755000

3

Design of thiazole orange oligonucleotide probes for detection of DNA and RNA by fluorescence and duplex melting.

Klimkowski P, De Ornellas S, Singleton D, El-Sagheer AH, Brown T. Klimkowski P, et al. Org Biomol Chem. 2019 Jun 28;17(24):5943-5950. doi: 10.1039/c9ob00885c. Epub 2019 Jun 3. Org Biomol Chem. 2019. PMID: 31157811 Free PMC article.

4

A Click Chemistry Approach to Targeted DNA Crosslinking with cis-Platinum(II)-Modified Triplex-Forming Oligonucleotides.

Hennessy J, McGorman B, Molphy Z, Farrell NP, Singleton D, Brown T, Kellett A. Hennessy J, et al. Angew Chem Int Ed Engl. 2022 Jan 17;61(3):e202110455. doi: 10.1002/anie.202110455. Epub 2021 Dec 3. Angew Chem Int Ed Engl. 2022. PMID: 34652881 Free PMC article.

5

An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.

Baker YR, Thorpe C, Chen J, Poller LM, Cox L, Kumar P, Lim WF, Lie L, McClorey G, Epple S, Singleton D, McDonough MA, Hardwick JS, Christensen KE, Wood MJA, Hall JP, El-Sagheer AH, Brown T. Baker YR, et al. Nat Commun. 2022 Jul 12;13(1):4036. doi: 10.1038/s41467-022-31636-2. Nat Commun. 2022. PMID: 35821218 Free PMC article.

6

A DNA based five-state switch with programmed reversibility.

Burns JR, Preus S, Singleton DG, Stulz E. Burns JR, et al. Among authors: singleton dg. Chem Commun (Camb). 2012 Nov 21;48(90):11088-90. doi: 10.1039/c2cc35799b. Epub 2012 Oct 9. Chem Commun (Camb). 2012. PMID: 23047524

7

Increased duplex stabilization in porphyrin-LNA zipper arrays with structure dependent exciton coupling.

Singleton DG, Hussain R, Siligardi G, Kumar P, Hrdlicka PJ, Berova N, Stulz E. Singleton DG, et al. Org Biomol Chem. 2016 Jan 7;14(1):149-57. doi: 10.1039/c5ob01681a. Epub 2015 Sep 29. Org Biomol Chem. 2016. PMID: 26416024 Free PMC article.

8

End-capped HyBeacon probes for the analysis of human genetic polymorphisms related to warfarin metabolism.

Ben Gaied N, Richardson JA, Singleton DG, Zhao Z, French D, Brown T. Ben Gaied N, et al. Among authors: singleton dg. Org Biomol Chem. 2010 Jun 21;8(12):2728-34. doi: 10.1039/c001177k. Epub 2010 Apr 14. Org Biomol Chem. 2010. PMID: 20393654

9

5-Formylcytosine does not change the global structure of DNA.

Hardwick JS, Ptchelkine D, El-Sagheer AH, Tear I, Singleton D, Phillips SEV, Lane AN, Brown T. Hardwick JS, et al. Nat Struct Mol Biol. 2017 Jun;24(6):544-552. doi: 10.1038/nsmb.3411. Epub 2017 May 15. Nat Struct Mol Biol. 2017. PMID: 28504696 Free PMC article.

10

A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA.

Grabowska I, Singleton DG, Stachyra A, Góra-Sochacka A, Sirko A, Zagórski-Ostoja W, Radecka H, Stulz E, Radecki J. Grabowska I, et al. Among authors: singleton dg. Chem Commun (Camb). 2014 Apr 25;50(32):4196-9. doi: 10.1039/c4cc00172a. Chem Commun (Camb). 2014. PMID: 24633340 Free article.

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