Simmons L - Search Results

1

Slashing the timelines: Opting to generate high-titer clonal lines faster via viability-based single cell sorting.

Misaghi S, Shaw D, Louie S, Nava A, Simmons L, Snedecor B, Poon C, Paw JS, Gilmour-Appling L, Cupp JE. Misaghi S, et al. Among authors: simmons l. Biotechnol Prog. 2016 Jan-Feb;32(1):198-207. doi: 10.1002/btpr.2204. Epub 2015 Dec 12. Biotechnol Prog. 2016. PMID: 26587808

2

Tailoring translational strength using Kozak sequence variants improves bispecific antibody assembly and reduces product-related impurities in CHO cells.

Blanco N, Williams AJ, Tang D, Zhan D, Misaghi S, Kelley RF, Simmons LC. Blanco N, et al. Biotechnol Bioeng. 2020 Jul;117(7):1946-1960. doi: 10.1002/bit.27347. Epub 2020 Apr 21. Biotechnol Bioeng. 2020. PMID: 32246763

3

Capillary size exclusion chromatography with picogram sensitivity for analysis of monoclonal antibodies purified from harvested cell culture fluid.

Rea JC, Moreno GT, Vampola L, Lou Y, van Haan B, Tremintin G, Simmons L, Nava A, Wang YJ, Farnan D. Rea JC, et al. Among authors: simmons l. J Chromatogr A. 2012 Jan 6;1219:140-6. doi: 10.1016/j.chroma.2011.11.025. Epub 2011 Nov 22. J Chromatogr A. 2012. PMID: 22153816

4

Translational level is a critical factor for the secretion of heterologous proteins in Escherichia coli.

Simmons LC, Yansura DG. Simmons LC, et al. Nat Biotechnol. 1996 May;14(5):629-34. doi: 10.1038/nbt0596-629. Nat Biotechnol. 1996. PMID: 9630956

5

Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons.

Horger BA, Nishimura MC, Armanini MP, Wang LC, Poulsen KT, Rosenblad C, Kirik D, Moffat B, Simmons L, Johnson E Jr, Milbrandt J, Rosenthal A, Bjorklund A, Vandlen RA, Hynes MA, Phillips HS. Horger BA, et al. Among authors: simmons l. J Neurosci. 1998 Jul 1;18(13):4929-37. doi: 10.1523/JNEUROSCI.18-13-04929.1998. J Neurosci. 1998. PMID: 9634558 Free PMC article.

6

Expression of full-length immunoglobulins in Escherichia coli: rapid and efficient production of aglycosylated antibodies.

Simmons LC, Reilly D, Klimowski L, Raju TS, Meng G, Sims P, Hong K, Shields RL, Damico LA, Rancatore P, Yansura DG. Simmons LC, et al. J Immunol Methods. 2002 May 1;263(1-2):133-47. doi: 10.1016/s0022-1759(02)00036-4. J Immunol Methods. 2002. PMID: 12009210

7

A mutant of melanoma growth stimulating activity does not activate neutrophils but blocks erythrocyte invasion by malaria.

Hesselgesser J, Chitnis CE, Miller LH, Yansura DG, Simmons LC, Fairbrother WJ, Kotts C, Wirth C, Gillece-Castro BL, Horuk R. Hesselgesser J, et al. Among authors: simmons lc. J Biol Chem. 1995 May 12;270(19):11472-6. doi: 10.1074/jbc.270.19.11472. J Biol Chem. 1995. PMID: 7744785 Free article.

8

A His19 to Ala mutant of melanoma growth-stimulating activity is a partial antagonist of the CXCR2 receptor.

Baly DL, Horuk R, Yansura DG, Simmons LC, Fairbrother WJ, Kotts C, Wirth CM, Gillece-Castro BL, Toy K, Hesselgesser J, Allison DE. Baly DL, et al. Among authors: simmons lc. J Immunol. 1998 Nov 1;161(9):4944-9. J Immunol. 1998. PMID: 9794430

9

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A. Clark HF, et al. Among authors: simmons l. Genome Res. 2003 Oct;13(10):2265-70. doi: 10.1101/gr.1293003. Epub 2003 Sep 15. Genome Res. 2003. PMID: 12975309 Free PMC article.

10

GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle.

Henderson CE, Phillips HS, Pollock RA, Davies AM, Lemeulle C, Armanini M, Simmons L, Moffet B, Vandlen RA, Simpson LC corrected to Simmons L, Koliatsos VE, Rosenthal A, et al. Henderson CE, et al. Among authors: simmons l. Science. 1994 Nov 11;266(5187):1062-4. doi: 10.1126/science.7973664. Science. 1994. PMID: 7973664

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