Sieber SA - Search Results

1

Bifunctional Duocarmycin Analogues as Inhibitors of Protein Tyrosine Kinases.

De Ford C, Penchalaiah K, Kreft A, Humar M, Heydenreuter W, Kangani M, Sieber SA, Tietze LF, Merfort I. De Ford C, et al. Among authors: sieber sa. J Nat Prod. 2019 Jan 25;82(1):16-26. doi: 10.1021/acs.jnatprod.8b00233. Epub 2019 Jan 8. J Nat Prod. 2019. PMID: 30620194

2

Duocarmycin analogues target aldehyde dehydrogenase 1 in lung cancer cells.

Wirth T, Schmuck K, Tietze LF, Sieber SA. Wirth T, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2012 Mar 19;51(12):2874-7. doi: 10.1002/anie.201106334. Epub 2012 Feb 14. Angew Chem Int Ed Engl. 2012. PMID: 22334487 No abstract available.

3

Chemical proteomics: ligation and cleavage of protein modifications.

Rudolf GC, Heydenreuter W, Sieber SA. Rudolf GC, et al. Among authors: sieber sa. Curr Opin Chem Biol. 2013 Feb;17(1):110-7. doi: 10.1016/j.cbpa.2012.11.007. Epub 2012 Dec 28. Curr Opin Chem Biol. 2013. PMID: 23273612 Review.

4

Duocarmycin analogues without a DNA-binding indole unit associate with aldehyde dehydrogenase 1A1 and not DNA: a reply.

Tietze LF, Sieber SA. Tietze LF, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2013 May 17;52(21):5447-9. doi: 10.1002/anie.201301923. Epub 2013 Apr 24. Angew Chem Int Ed Engl. 2013. PMID: 23616344 No abstract available.

5

The two faces of potent antitumor duocarmycin-based drugs: a structural dissection reveals disparate motifs for DNA versus aldehyde dehydrogenase 1 affinity.

Wirth T, Pestel GF, Ganal V, Kirmeier T, Schuberth I, Rein T, Tietze LF, Sieber SA. Wirth T, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2013 Jul 1;52(27):6921-5. doi: 10.1002/anie.201208941. Epub 2013 May 16. Angew Chem Int Ed Engl. 2013. PMID: 23681547 No abstract available.

6

Alkynol natural products target ALDH2 in cancer cells by irreversible binding to the active site.

Heydenreuter W, Kunold E, Sieber SA. Heydenreuter W, et al. Among authors: sieber sa. Chem Commun (Camb). 2015 Nov 11;51(87):15784-7. doi: 10.1039/c5cc06424d. Chem Commun (Camb). 2015. PMID: 26365706

7

Structural, Biochemical, and Computational Studies Reveal the Mechanism of Selective Aldehyde Dehydrogenase 1A1 Inhibition by Cytotoxic Duocarmycin Analogues.

Koch MF, Harteis S, Blank ID, Pestel G, Tietze LF, Ochsenfeld C, Schneider S, Sieber SA. Koch MF, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13550-4. doi: 10.1002/anie.201505749. Epub 2015 Sep 16. Angew Chem Int Ed Engl. 2015. PMID: 26373694

8

A Whole Proteome Inventory of Background Photocrosslinker Binding.

Kleiner P, Heydenreuter W, Stahl M, Korotkov VS, Sieber SA. Kleiner P, et al. Among authors: sieber sa. Angew Chem Int Ed Engl. 2017 Jan 24;56(5):1396-1401. doi: 10.1002/anie.201605993. Epub 2016 Dec 16. Angew Chem Int Ed Engl. 2017. PMID: 27981680

9

Influence of wing-tip substituents and reaction conditions on the structure, properties and cytotoxicity of Ag(i)- and Au(i)-bis(NHC) complexes.

Rieb J, Dominelli B, Mayer D, Jandl C, Drechsel J, Heydenreuter W, Sieber SA, Kühn FE. Rieb J, et al. Among authors: sieber sa. Dalton Trans. 2017 Feb 21;46(8):2722-2735. doi: 10.1039/c6dt04559f. Dalton Trans. 2017. PMID: 28174778

10

Profiling withanolide A for therapeutic targets in neurodegenerative diseases.

Crane EA, Heydenreuter W, Beck KR, Strajhar P, Vomacka J, Smiesko M, Mons E, Barth L, Neuburger M, Vedani A, Odermatt A, Sieber SA, Gademann K. Crane EA, et al. Among authors: sieber sa. Bioorg Med Chem. 2019 Jun 15;27(12):2508-2520. doi: 10.1016/j.bmc.2019.03.022. Epub 2019 Mar 13. Bioorg Med Chem. 2019. PMID: 30929949 Free article.

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