Sheridan RM - Search Results

1

Optimizing natural products by biosynthetic engineering: discovery of nonquinone Hsp90 inhibitors.

Zhang MQ, Gaisser S, Nur-E-Alam M, Sheehan LS, Vousden WA, Gaitatzis N, Peck G, Coates NJ, Moss SJ, Radzom M, Foster TA, Sheridan RM, Gregory MA, Roe SM, Prodromou C, Pearl L, Boyd SM, Wilkinson B, Martin CJ. Zhang MQ, et al. Among authors: sheridan rm. J Med Chem. 2008 Sep 25;51(18):5494-7. doi: 10.1021/jm8006068. J Med Chem. 2008. PMID: 18800759

2

Heterologous expression in Saccharopolyspora erythraea of a pentaketide synthase derived from the spinosyn polyketide synthase.

Martin CJ, Timoney MC, Sheridan RM, Kendrew SG, Wilkinson B, Staunton JC, Leadlay PF. Martin CJ, et al. Among authors: sheridan rm. Org Biomol Chem. 2003 Dec 7;1(23):4144-7. doi: 10.1039/b310740j. Epub 2003 Oct 29. Org Biomol Chem. 2003. PMID: 14685317

3

Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain.

Wilkinson B, Gregory MA, Moss SJ, Carletti I, Sheridan RM, Kaja A, Ward M, Olano C, Mendez C, Salas JA, Leadlay PF, vanGinckel R, Zhang MQ. Wilkinson B, et al. Among authors: sheridan rm. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5814-7. doi: 10.1016/j.bmcl.2006.08.073. Epub 2006 Sep 8. Bioorg Med Chem Lett. 2006. PMID: 16962775

4

Rapamycin biosynthesis: Elucidation of gene product function.

Gregory MA, Hong H, Lill RE, Gaisser S, Petkovic H, Low L, Sheehan LS, Carletti I, Ready SJ, Ward MJ, Kaja AL, Weston AJ, Challis IR, Leadlay PF, Martin CJ, Wilkinson B, Sheridan RM. Gregory MA, et al. Among authors: sheridan rm. Org Biomol Chem. 2006 Oct 7;4(19):3565-8. doi: 10.1039/b608813a. Epub 2006 Aug 22. Org Biomol Chem. 2006. PMID: 16990929

5

Engineered biosynthesis of hybrid macrolide polyketides containing D-angolosamine and D-mycaminose moieties.

Schell U, Haydock SF, Kaja AL, Carletti I, Lill RE, Read E, Sheehan LS, Low L, Fernandez MJ, Grolle F, McArthur HA, Sheridan RM, Leadlay PF, Wilkinson B, Gaisser S. Schell U, et al. Among authors: sheridan rm. Org Biomol Chem. 2008 Sep 21;6(18):3315-27. doi: 10.1039/b807914e. Epub 2008 Jul 28. Org Biomol Chem. 2008. PMID: 18802638

6

Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.

Gregory MA, Petkovic H, Lill RE, Moss SJ, Wilkinson B, Gaisser S, Leadlay PF, Sheridan RM. Gregory MA, et al. Among authors: sheridan rm. Angew Chem Int Ed Engl. 2005 Jul 25;44(30):4757-60. doi: 10.1002/anie.200462784. Angew Chem Int Ed Engl. 2005. PMID: 15977283 No abstract available.

7

Engineering of the spinosyn PKS: directing starter unit incorporation.

Sheehan LS, Lill RE, Wilkinson B, Sheridan RM, Vousden WA, Kaja AL, Crouse GD, Gifford J, Graupner PR, Karr L, Lewer P, Sparks TC, Leadlay PF, Waldron C, Martin CJ. Sheehan LS, et al. Among authors: sheridan rm. J Nat Prod. 2006 Dec;69(12):1702-10. doi: 10.1021/np0602517. J Nat Prod. 2006. PMID: 17190446

8

Recombinant strains for the enhanced production of bioengineered rapalogs.

Kendrew SG, Petkovic H, Gaisser S, Ready SJ, Gregory MA, Coates NJ, Nur-E-Alam M, Warneck T, Suthar D, Foster TA, McDonald L, Schlingman G, Koehn FE, Skotnicki JS, Carter GT, Moss SJ, Zhang MQ, Martin CJ, Sheridan RM, Wilkinson B. Kendrew SG, et al. Among authors: sheridan rm. Metab Eng. 2013 Jan;15:167-73. doi: 10.1016/j.ymben.2012.11.001. Epub 2012 Nov 17. Metab Eng. 2013. PMID: 23164580

9

Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Moss SJ, Carletti I, Olano C, Sheridan RM, Ward M, Math V, Nur-E-Alam M, Braña AF, Zhang MQ, Leadlay PF, Méndez C, Salas JA, Wilkinson B. Moss SJ, et al. Among authors: sheridan rm. Chem Commun (Camb). 2006 Jun 14;(22):2341-3. doi: 10.1039/b602931k. Epub 2006 May 11. Chem Commun (Camb). 2006. PMID: 16733573

10

Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272.

Gaisser S, Kellenberger L, Kaja AL, Weston AJ, Lill RE, Wirtz G, Kendrew SG, Low L, Sheridan RM, Wilkinson B, Galloway IS, Stutzman-Engwall K, McArthur HA, Staunton J, Leadlay PF. Gaisser S, et al. Among authors: sheridan rm. Org Biomol Chem. 2003 Aug 21;1(16):2840-7. doi: 10.1039/b304022d. Org Biomol Chem. 2003. PMID: 12968333

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