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C-to-G editing generates double-strand breaks causing deletion, transversion and translocation.
Huang ME, Qin Y, Shang Y, Hao Q, Zhan C, Lian C, Luo S, Liu LD, Zhang S, Zhang Y, Wo Y, Li N, Wu S, Gui T, Wang B, Luo Y, Cai Y, Liu X, Xu Z, Dai P, Li S, Zhang L, Dong J, Wang J, Zheng X, Xu Y, Sun Y, Wu W, Yeap LS, Meng FL. Huang ME, et al. Among authors: shang y. Nat Cell Biol. 2024 Feb;26(2):294-304. doi: 10.1038/s41556-023-01342-2. Epub 2024 Jan 23. Nat Cell Biol. 2024. PMID: 38263276
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.
Liu X, Liu T, Shang Y, Dai P, Zhang W, Lee BJ, Huang M, Yang D, Wu Q, Liu LD, Zheng X, Zhou BO, Dong J, Yeap LS, Hu J, Xiao T, Zha S, Casellas R, Liu XS, Meng FL. Liu X, et al. Among authors: shang y. Cell Res. 2020 Sep;30(9):732-744. doi: 10.1038/s41422-020-0328-3. Epub 2020 Apr 30. Cell Res. 2020. PMID: 32355287 Free PMC article.
REV7 is required for processing AID initiated DNA lesions in activated B cells.
Yang D, Sun Y, Chen J, Zhang Y, Fan S, Huang M, Xie X, Cai Y, Shang Y, Gui T, Sun L, Hu J, Dong J, Yeap LS, Wang X, Xiao W, Meng FL. Yang D, et al. Among authors: shang y. Nat Commun. 2020 Jun 4;11(1):2812. doi: 10.1038/s41467-020-16632-8. Nat Commun. 2020. PMID: 32499490 Free PMC article.
Global detection of DNA repair outcomes induced by CRISPR-Cas9.
Liu M, Zhang W, Xin C, Yin J, Shang Y, Ai C, Li J, Meng FL, Hu J. Liu M, et al. Among authors: shang y. Nucleic Acids Res. 2021 Sep 7;49(15):8732-8742. doi: 10.1093/nar/gkab686. Nucleic Acids Res. 2021. PMID: 34365511 Free PMC article.
Nanoparticles for inducing Gaucher disease-like damage in cancer cells.
Yue C, Lu W, Fan S, Huang Z, Yang J, Dong H, Zhang X, Shang Y, Lai W, Li D, Dong T, Yuan A, Wu J, Kang L, Hu Y. Yue C, et al. Among authors: shang y. Nat Nanotechnol. 2024 May 13. doi: 10.1038/s41565-024-01668-4. Online ahead of print. Nat Nanotechnol. 2024. PMID: 38740934
3,955 results