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Page 1
Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors.
Jayan J, Chandran N, Thekkantavida AC, Abdelgawad MA, Ghoneim MM, Shaker ME, Uniyal P, Benny F, Zachariah SM, Kumar S, Kim H, Mathew B. Jayan J, et al. Among authors: shaker me. ACS Omega. 2023 Oct 3;8(41):37731-37751. doi: 10.1021/acsomega.3c05883. eCollection 2023 Oct 17. ACS Omega. 2023. PMID: 37867639 Free PMC article. Review.
Design, synthesis, and biological evaluation of novel pyrido-dipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells.
Abdelgawad MA, Mohamed FEA, Lamie PF, Bukhari SNA, Al-Sanea MM, Musa A, Elmowafy M, Nayl AA, Karam Farag A, Ali SM, Shaker ME, Omar HA, Abdelhameid MK, Kandeel MM. Abdelgawad MA, et al. Among authors: shaker me. Bioorg Chem. 2022 May;122:105752. doi: 10.1016/j.bioorg.2022.105752. Epub 2022 Mar 22. Bioorg Chem. 2022. PMID: 35339926
New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling.
Abdelgawad MA, Bukhari SNA, Musa A, Elmowafy M, Elkomy MH, Nayl AA, El-Ghorab AH, Alsohaimi IH, Abdel-Bakky MS, Althobaiti IO, Altaleb HA, Omar HA, Abdelazeem AH, Zaki MA, Shaker ME, Elshemy HAH. Abdelgawad MA, et al. Among authors: shaker me. Pharmaceuticals (Basel). 2022 Sep 10;15(9):1134. doi: 10.3390/ph15091134. Pharmaceuticals (Basel). 2022. PMID: 36145355 Free PMC article.
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.
Musa A, Ihmaid SK, Hughes DL, Said MA, Abulkhair HS, El-Ghorab AH, Abdelgawad MA, Shalaby K, Shaker ME, Alharbi KS, Alotaibi NH, Kays DL, Taylor LJ, Parambi DGT, Alzarea SI, Al-Karmalawy AA, Ahmed HEA, El-Agrody AM. Musa A, et al. Among authors: shaker me. J Biomol Struct Dyn. 2023;41(21):12411-12425. doi: 10.1080/07391102.2023.2167000. Epub 2023 Jan 20. J Biomol Struct Dyn. 2023. PMID: 36661285
Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease.
Manoharan A, Oh JM, Benny F, Kumar S, Abdelgawad MA, Ghoneim MM, Shaker ME, El-Sherbiny M, Almohaimeed HM, Gahtori P, Kim H, Mathew B. Manoharan A, et al. Among authors: shaker me. Molecules. 2023 Aug 21;28(16):6167. doi: 10.3390/molecules28166167. Molecules. 2023. PMID: 37630420 Free PMC article.
46 results