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Senescent cells harbour features of the cancer epigenome.
Cruickshanks HA, McBryan T, Nelson DM, Vanderkraats ND, Shah PP, van Tuyn J, Singh Rai T, Brock C, Donahue G, Dunican DS, Drotar ME, Meehan RR, Edwards JR, Berger SL, Adams PD. Cruickshanks HA, et al. Among authors: shah pp. Nat Cell Biol. 2013 Dec;15(12):1495-506. doi: 10.1038/ncb2879. Epub 2013 Nov 24. Nat Cell Biol. 2013. PMID: 24270890 Free PMC article.
Lysosome-mediated processing of chromatin in senescence.
Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson DM, Rai TS, Shah PP, Hewitt G, Korolchuk VI, Passos JF, Wu H, Berger SL, Adams PD. Ivanov A, et al. Among authors: shah pp. J Cell Biol. 2013 Jul 8;202(1):129-43. doi: 10.1083/jcb.201212110. Epub 2013 Jul 1. J Cell Biol. 2013. PMID: 23816621 Free PMC article.
Autophagy mediates degradation of nuclear lamina.
Dou Z, Xu C, Donahue G, Shimi T, Pan JA, Zhu J, Ivanov A, Capell BC, Drake AM, Shah PP, Catanzaro JM, Ricketts MD, Lamark T, Adam SA, Marmorstein R, Zong WX, Johansen T, Goldman RD, Adams PD, Berger SL. Dou Z, et al. Among authors: shah pp. Nature. 2015 Nov 5;527(7576):105-9. doi: 10.1038/nature15548. Epub 2015 Oct 28. Nature. 2015. PMID: 26524528 Free PMC article.
H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis.
Hu J, Donahue G, Dorsey J, Govin J, Yuan Z, Garcia BA, Shah PP, Berger SL. Hu J, et al. Among authors: shah pp. Cell Rep. 2015 Dec 1;13(9):1772-80. doi: 10.1016/j.celrep.2015.10.070. Epub 2015 Nov 25. Cell Rep. 2015. PMID: 26628362 Free PMC article.
MLL1 is essential for the senescence-associated secretory phenotype.
Capell BC, Drake AM, Zhu J, Shah PP, Dou Z, Dorsey J, Simola DF, Donahue G, Sammons M, Rai TS, Natale C, Ridky TW, Adams PD, Berger SL. Capell BC, et al. Among authors: shah pp. Genes Dev. 2016 Feb 1;30(3):321-36. doi: 10.1101/gad.271882.115. Genes Dev. 2016. PMID: 26833731 Free PMC article.
Epigenetic Mechanisms of Longevity and Aging.
Sen P, Shah PP, Nativio R, Berger SL. Sen P, et al. Among authors: shah pp. Cell. 2016 Aug 11;166(4):822-839. doi: 10.1016/j.cell.2016.07.050. Cell. 2016. PMID: 27518561 Free PMC article. Review.
High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: shah pp. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
199 results