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Manipulating the Mediator complex to induce naïve pluripotency.
Lynch CJ, Bernad R, Calvo I, Serrano M. Lynch CJ, et al. Among authors: serrano m. Exp Cell Res. 2020 Oct 15;395(2):112215. doi: 10.1016/j.yexcr.2020.112215. Epub 2020 Aug 6. Exp Cell Res. 2020. PMID: 32771524 Free PMC article. Review.
The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity.
Lynch CJ, Bernad R, Calvo I, Nóbrega-Pereira S, Ruiz S, Ibarz N, Martinez-Val A, Graña-Castro O, Gómez-López G, Andrés-León E, Espinosa Angarica V, Del Sol A, Ortega S, Fernandez-Capetillo O, Rojo E, Munoz J, Serrano M. Lynch CJ, et al. Among authors: serrano m. Cell Rep. 2018 Jan 9;22(2):396-410. doi: 10.1016/j.celrep.2017.12.062. Cell Rep. 2018. PMID: 29320736 Free PMC article.
Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells.
Aksoy I, Rognard C, Moulin A, Marcy G, Masfaraud E, Wianny F, Cortay V, Bellemin-Ménard A, Doerflinger N, Dirheimer M, Mayère C, Bourillot PY, Lynch C, Raineteau O, Joly T, Dehay C, Serrano M, Afanassieff M, Savatier P. Aksoy I, et al. Among authors: serrano m. Stem Cell Reports. 2021 Jan 12;16(1):56-74. doi: 10.1016/j.stemcr.2020.12.004. Epub 2020 Dec 30. Stem Cell Reports. 2021. PMID: 33382978 Free PMC article.
Deciphering the roadmap of in vivo reprogramming toward pluripotency.
Chondronasiou D, Martínez de Villarreal J, Melendez E, Lynch CJ, Pozo ND, Kovatcheva M, Aguilera M, Prats N, Real FX, Serrano M. Chondronasiou D, et al. Among authors: serrano m. Stem Cell Reports. 2022 Nov 8;17(11):2501-2517. doi: 10.1016/j.stemcr.2022.09.009. Epub 2022 Oct 20. Stem Cell Reports. 2022. PMID: 36270281 Free PMC article.
p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.
Li H, Collado M, Villasante A, Matheu A, Lynch CJ, Cañamero M, Rizzoti K, Carneiro C, Martínez G, Vidal A, Lovell-Badge R, Serrano M. Li H, et al. Among authors: serrano m. Cell Stem Cell. 2012 Dec 7;11(6):845-52. doi: 10.1016/j.stem.2012.09.014. Cell Stem Cell. 2012. PMID: 23217425 Free PMC article.
AAVvector-mediated in vivo reprogramming into pluripotency.
Senís E, Mosteiro L, Wilkening S, Wiedtke E, Nowrouzi A, Afzal S, Fronza R, Landerer H, Abad M, Niopek D, Schmidt M, Serrano M, Grimm D. Senís E, et al. Among authors: serrano m. Nat Commun. 2018 Jul 9;9(1):2651. doi: 10.1038/s41467-018-05059-x. Nat Commun. 2018. PMID: 29985406 Free PMC article.
Cellular Senescence: Defining a Path Forward.
Gorgoulis V, Adams PD, Alimonti A, Bennett DC, Bischof O, Bishop C, Campisi J, Collado M, Evangelou K, Ferbeyre G, Gil J, Hara E, Krizhanovsky V, Jurk D, Maier AB, Narita M, Niedernhofer L, Passos JF, Robbins PD, Schmitt CA, Sedivy J, Vougas K, von Zglinicki T, Zhou D, Serrano M, Demaria M. Gorgoulis V, et al. Among authors: serrano m. Cell. 2019 Oct 31;179(4):813-827. doi: 10.1016/j.cell.2019.10.005. Cell. 2019. PMID: 31675495 Free article. Review.
1,950 results