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IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin-directed vascular barrier disruption.
Langer V, Vivi E, Regensburger D, Winkler TH, Waldner MJ, Rath T, Schmid B, Skottke L, Lee S, Jeon NL, Wohlfahrt T, Kramer V, Tripal P, Schumann M, Kersting S, Handtrack C, Geppert CI, Suchowski K, Adams RH, Becker C, Ramming A, Naschberger E, Britzen-Laurent N, Stürzl M. Langer V, et al. Among authors: schmid b. J Clin Invest. 2019 Nov 1;129(11):4691-4707. doi: 10.1172/JCI124884. J Clin Invest. 2019. PMID: 31566580 Free PMC article. Clinical Trial.
A New Fluorogenic Small-Molecule Labeling Tool for Surface Diffusion Analysis and Advanced Fluorescence Imaging of β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Based on Silicone Rhodamine: SiR-BACE1.
Karch S, Broichhagen J, Schneider J, Böning D, Hartmann S, Schmid B, Tripal P, Palmisano R, Alzheimer C, Johnsson K, Huth T. Karch S, et al. Among authors: schmid b. J Med Chem. 2018 Jul 26;61(14):6121-6139. doi: 10.1021/acs.jmedchem.8b00387. Epub 2018 Jul 10. J Med Chem. 2018. PMID: 29939737
STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.
Heichler C, Scheibe K, Schmied A, Geppert CI, Schmid B, Wirtz S, Thoma OM, Kramer V, Waldner MJ, Büttner C, Farin HF, Pešić M, Knieling F, Merkel S, Grüneboom A, Gunzer M, Grützmann R, Rose-John S, Koralov SB, Kollias G, Vieth M, Hartmann A, Greten FR, Neurath MF, Neufert C. Heichler C, et al. Among authors: schmid b. Gut. 2020 Jul;69(7):1269-1282. doi: 10.1136/gutjnl-2019-319200. Epub 2019 Nov 4. Gut. 2020. PMID: 31685519
Arginase impedes the resolution of colitis by altering the microbiome and metabolome.
Baier J, Gänsbauer M, Giessler C, Arnold H, Muske M, Schleicher U, Lukassen S, Ekici A, Rauh M, Daniel C, Hartmann A, Schmid B, Tripal P, Dettmer K, Oefner PJ, Atreya R, Wirtz S, Bogdan C, Mattner J. Baier J, et al. Among authors: schmid b. J Clin Invest. 2020 Nov 2;130(11):5703-5720. doi: 10.1172/JCI126923. J Clin Invest. 2020. PMID: 32721946 Free PMC article.
Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease.
Regensburger D, Tenkerian C, Pürzer V, Schmid B, Wohlfahrt T, Stolzer I, López-Posadas R, Günther C, Waldner MJ, Becker C, Sticht H, Petter K, Flierl C, Gass T, Thoenissen T, Geppert CI, Britzen-Laurent N, Méniel VS, Ramming A, Stürzl M, Naschberger E. Regensburger D, et al. Among authors: schmid b. Inflamm Bowel Dis. 2021 Aug 19;27(9):1491-1502. doi: 10.1093/ibd/izaa346. Inflamm Bowel Dis. 2021. PMID: 33393634 Free PMC article.
767 results