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New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn.
Lang KL, da Rosa Guimarães T, Rocha Machado V, Zimmermann LA, Silva IT, Teixeira MR, Durán FJ, Palermo JA, Simões CM, Caro MS, Schenkel EP. Lang KL, et al. Among authors: schenkel ep. Planta Med. 2011 Sep;77(14):1648-51. doi: 10.1055/s-0030-1270962. Epub 2011 Apr 6. Planta Med. 2011. PMID: 21472651
Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model.
Marostica LL, de Barros ALB, Oliveira J, Salgado BS, Cassali GD, Leite EA, Cardoso VN, Lang KL, Caro MSB, Durán FJ, Schenkel EP, de Oliveira MC, Simões CMO. Marostica LL, et al. Among authors: schenkel ep. Toxicol Appl Pharmacol. 2017 Aug 15;329:272-281. doi: 10.1016/j.taap.2017.06.007. Epub 2017 Jun 10. Toxicol Appl Pharmacol. 2017. PMID: 28610991
Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol.
Lang KL, Silva IT, Zimmermann LA, Lhullier C, Mañalich Arana MV, Palermo JA, Falkenberg M, Simões CMO, Schenkel EP, Durán FJ. Lang KL, et al. Among authors: schenkel ep. Mar Drugs. 2012 Oct;10(10):2254-2264. doi: 10.3390/md10102254. Epub 2012 Oct 18. Mar Drugs. 2012. PMID: 23170082 Free PMC article.
Natural-product-inspired design and synthesis of two series of compounds active against Trypanosoma cruzi: Insights into structure-activity relationship, toxicity, and mechanism of action.
da Rosa R, Dambrós BP, Höehr de Moraes M, Grand L, Jacolot M, Popowycz F, Steindel M, Schenkel EP, Campos Bernardes LS. da Rosa R, et al. Among authors: schenkel ep. Bioorg Chem. 2022 Feb;119:105492. doi: 10.1016/j.bioorg.2021.105492. Epub 2021 Nov 15. Bioorg Chem. 2022. PMID: 34838333
85 results