Schüler H - Search Results

1

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities.

Đukić N, Strømland Ø, Elsborg JD, Munnur D, Zhu K, Schuller M, Chatrin C, Kar P, Duma L, Suyari O, Rack JGM, Baretić D, Crudgington DRK, Groslambert J, Fowler G, Wijngaarden S, Prokhorova E, Rehwinkel J, Schüler H, Filippov DV, Sanyal S, Ahel D, Nielsen ML, Smith R, Ahel I. Đukić N, et al. Among authors: schuler h. Sci Adv. 2023 Sep 15;9(37):eadi2687. doi: 10.1126/sciadv.adi2687. Epub 2023 Sep 13. Sci Adv. 2023. PMID: 37703374 Free PMC article.

2

PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.

Lindgren AE, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schüler H. Lindgren AE, et al. Among authors: schuler h. ACS Chem Biol. 2013 Aug 16;8(8):1698-703. doi: 10.1021/cb4002014. Epub 2013 Jun 25. ACS Chem Biol. 2013. PMID: 23742272

3

PARP14 Contributes to the Development of the Tumor-Associated Macrophage Phenotype.

Sturniolo I, Váróczy C, Regdon Z, Mázló A, Muzsai S, Bácsi A, Intili G, Hegedűs C, Boothby MR, Holechek J, Ferraris D, Schüler H, Virág L. Sturniolo I, et al. Among authors: schuler h. Int J Mol Sci. 2024 Mar 22;25(7):3601. doi: 10.3390/ijms25073601. Int J Mol Sci. 2024. PMID: 38612413 Free PMC article.

4

Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14.

Upton K, Meyers M, Thorsell AG, Karlberg T, Holechek J, Lease R, Schey G, Wolf E, Lucente A, Schüler H, Ferraris D. Upton K, et al. Among authors: schuler h. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2907-2911. doi: 10.1016/j.bmcl.2017.04.089. Epub 2017 Apr 29. Bioorg Med Chem Lett. 2017. PMID: 28495083

5

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

Loseva O, Jemth AS, Bryant HE, Schüler H, Lehtiö L, Karlberg T, Helleday T. Loseva O, et al. Among authors: schuler h. J Biol Chem. 2010 Mar 12;285(11):8054-60. doi: 10.1074/jbc.M109.077834. Epub 2010 Jan 11. J Biol Chem. 2010. PMID: 20064938 Free PMC article.

6

Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14.

Holechek J, Lease R, Thorsell AG, Karlberg T, McCadden C, Grant R, Keen A, Callahan E, Schüler H, Ferraris D. Holechek J, et al. Among authors: schuler h. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2050-2054. doi: 10.1016/j.bmcl.2018.04.056. Epub 2018 May 3. Bioorg Med Chem Lett. 2018. PMID: 29748053

7

Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.

Pinto AF, Schüler H. Pinto AF, et al. Among authors: schuler h. Curr Top Microbiol Immunol. 2015;384:153-66. doi: 10.1007/82_2014_417. Curr Top Microbiol Immunol. 2015. PMID: 25015788 Review.

8

PARP10 Multi-Site Auto- and Histone MARylation Visualized by Acid-Urea Gel Electrophoresis.

García-Saura AG, Schüler H. García-Saura AG, et al. Among authors: schuler h. Cells. 2021 Mar 15;10(3):654. doi: 10.3390/cells10030654. Cells. 2021. PMID: 33804157 Free PMC article.

9

MacroGreen, a simple tool for detection of ADP-ribosylated proteins.

García-Saura AG, Herzog LK, Dantuma NP, Schüler H. García-Saura AG, et al. Among authors: schuler h. Commun Biol. 2021 Jul 28;4(1):919. doi: 10.1038/s42003-021-02439-w. Commun Biol. 2021. PMID: 34321589 Free PMC article.

10

Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol.

Ekblad T, Verheugd P, Lindgren AE, Nyman T, Elofsson M, Schüler H. Ekblad T, et al. Among authors: schuler h. SLAS Discov. 2018 Apr;23(4):353-362. doi: 10.1177/2472555217750870. Epub 2018 Jan 9. SLAS Discov. 2018. PMID: 29316839 Free article.

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