Saphire EO - Search Results

1

Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium.

Callaway HM, Hastie KM, Schendel SL, Li H, Yu X, Shek J, Buck T, Hui S, Bedinger D, Troup C, Dennison SM, Li K, Alpert MD, Bailey CC, Benzeno S, Bonnevier JL, Chen JQ, Chen C, Cho H, Crompton PD, Dussupt V, Entzminger KC, Ezzyat Y, Fleming JK, Geukens N, Gilbert AE, Guan Y, Han X, Harvey CJ, Hatler JM, Howie B, Hu C, Huang A, Imbrechts M, Jin A, Kamachi N, Keitany G, Klinger M, Kolls JK, Krebs SJ, Li T, Luo F, Maruyama T, Meehl MA, Mendez-Rivera L, Musa A, Okumura CJ, Rubin BER, Sato AK, Shen M, Singh A, Song S, Tan J, Trimarchi JM, Upadhyay DP, Wang Y, Yu L, Yuan TZ, Yusko E, Peters B, Tomaras G, Saphire EO. Callaway HM, et al. Among authors: saphire eo. Cell Rep. 2023 Jan 31;42(1):112014. doi: 10.1016/j.celrep.2023.112014. Epub 2023 Jan 12. Cell Rep. 2023. PMID: 36681898 Free PMC article.

2

Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression.

Hastie KM, Kimberlin CR, Zandonatti MA, MacRae IJ, Saphire EO. Hastie KM, et al. Among authors: saphire eo. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2396-401. doi: 10.1073/pnas.1016404108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262835 Free PMC article.

3

Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding.

Hastie KM, Liu T, Li S, King LB, Ngo N, Zandonatti MA, Woods VL Jr, de la Torre JC, Saphire EO. Hastie KM, et al. Among authors: saphire eo. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19365-70. doi: 10.1073/pnas.1108515108. Epub 2011 Nov 14. Proc Natl Acad Sci U S A. 2011. PMID: 22084115 Free PMC article.

4

Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses.

Hastie KM, Bale S, Kimberlin CR, Saphire EO. Hastie KM, et al. Among authors: saphire eo. Curr Opin Virol. 2012 Apr;2(2):151-6. doi: 10.1016/j.coviro.2012.01.003. Epub 2012 Jan 28. Curr Opin Virol. 2012. PMID: 22482712 Free PMC article. Review.

5

Structural basis for the dsRNA specificity of the Lassa virus NP exonuclease.

Hastie KM, King LB, Zandonatti MA, Saphire EO. Hastie KM, et al. Among authors: saphire eo. PLoS One. 2012;7(8):e44211. doi: 10.1371/journal.pone.0044211. Epub 2012 Aug 28. PLoS One. 2012. PMID: 22937163 Free PMC article.

6

Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression.

West BR, Hastie KM, Saphire EO. West BR, et al. Among authors: saphire eo. Acta Crystallogr D Biol Crystallogr. 2014 Jun;70(Pt 6):1764-9. doi: 10.1107/S1399004714007883. Epub 2014 May 30. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24914986 Free PMC article.

7

Mechanism of human antibody-mediated neutralization of Marburg virus.

Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE Jr. Flyak AI, et al. Among authors: saphire eo. Cell. 2015 Feb 26;160(5):893-903. doi: 10.1016/j.cell.2015.01.031. Cell. 2015. PMID: 25723164 Free PMC article.

8

Potent Antibody Protection against an Emerging Alphavirus Threat.

Kielian M, Saphire EO. Kielian M, et al. Among authors: saphire eo. Cell. 2015 Nov 19;163(5):1053-1054. doi: 10.1016/j.cell.2015.11.006. Cell. 2015. PMID: 26590413 Free article.

9

Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z.

Hastie KM, Zandonatti M, Liu T, Li S, Woods VL Jr, Saphire EO. Hastie KM, et al. Among authors: saphire eo. J Virol. 2016 Apr 14;90(9):4556-62. doi: 10.1128/JVI.02896-15. Print 2016 May. J Virol. 2016. PMID: 26912609 Free PMC article.

10

Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV.

Hastie KM, Igonet S, Sullivan BM, Legrand P, Zandonatti MA, Robinson JE, Garry RF, Rey FA, Oldstone MB, Saphire EO. Hastie KM, et al. Among authors: saphire eo. Nat Struct Mol Biol. 2016 Jun;23(6):513-521. doi: 10.1038/nsmb.3210. Epub 2016 Apr 25. Nat Struct Mol Biol. 2016. PMID: 27111888 Free PMC article.

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