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SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway.
Santos-Barriopedro I, Bosch-Presegué L, Marazuela-Duque A, de la Torre C, Colomer C, Vazquez BN, Fuhrmann T, Martínez-Pastor B, Lu W, Braun T, Bober E, Jenuwein T, Serrano L, Esteller M, Chen Z, Barceló-Batllori S, Mostoslavsky R, Espinosa L, Vaquero A. Santos-Barriopedro I, et al. Nat Commun. 2018 Jan 9;9(1):101. doi: 10.1038/s41467-017-02586-x. Nat Commun. 2018. PMID: 29317652 Free PMC article.
Complex role of SIRT6 in NF-κB pathway regulation.
Santos-Barriopedro I, Vaquero A. Santos-Barriopedro I, et al. Mol Cell Oncol. 2018 May 24;5(4):e1445942. doi: 10.1080/23723556.2018.1445942. eCollection 2018. Mol Cell Oncol. 2018. PMID: 30250909 Free PMC article.
A big step for SIRT7, one giant leap for Sirtuins… in cancer.
Martínez-Redondo P, Santos-Barriopedro I, Vaquero A. Martínez-Redondo P, et al. Among authors: santos barriopedro i. Cancer Cell. 2012 Jun 12;21(6):719-21. doi: 10.1016/j.ccr.2012.05.028. Cancer Cell. 2012. PMID: 22698398 Free article.
A synthetic mRNA cell reprogramming method using CYCLIN D1 promotes DNA repair, generating improved genetically stable human induced pluripotent stem cells.
Alvarez-Palomo AB, Requena-Osete J, Delgado-Morales R, Moreno-Manzano V, Grau-Bove C, Tejera AM, Otero MJ, Barrot C, Santos-Barriopedro I, Vaquero A, Mezquita-Pla J, Moran S, Naya CH, Garcia-Martínez I, Pérez FV, Blasco MA, Esteller M, Edel MJ. Alvarez-Palomo AB, et al. Among authors: santos barriopedro i. Stem Cells. 2021 Jul;39(7):866-881. doi: 10.1002/stem.3358. Epub 2021 Mar 3. Stem Cells. 2021. PMID: 33621399
Histone methyltransferase Suv39h1 deficiency prevents Myc-induced chromosomal instability in murine myeloid leukemias.
Vajen B, Modlich U, Schienke A, Wolf S, Skawran B, Hofmann W, Büsche G, Kreipe H, Baum C, Santos-Barriopedro I, Vaquero A, Schlegelberger B, Rudolph C. Vajen B, et al. Among authors: santos barriopedro i. Genes Chromosomes Cancer. 2013 Apr;52(4):423-30. doi: 10.1002/gcc.22040. Epub 2013 Jan 23. Genes Chromosomes Cancer. 2013. PMID: 23340989
Off-the-shelf proximity biotinylation using ProtA-TurboID.
Santos-Barriopedro I, van Mierlo G, Vermeulen M. Santos-Barriopedro I, et al. Nat Protoc. 2023 Jan;18(1):36-57. doi: 10.1038/s41596-022-00748-w. Epub 2022 Oct 12. Nat Protoc. 2023. PMID: 36224470 Review.