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TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.
Chen L, Roake CM, Maccallini P, Bavasso F, Dehghannasiri R, Santonicola P, Mendoza-Ferreira N, Scatolini L, Rizzuti L, Esposito A, Gallotta I, Francia S, Cacchione S, Galati A, Palumbo V, Kobin MA, Tartaglia GG, Colantoni A, Proietti G, Wu Y, Hammerschmidt M, De Pittà C, Sales G, Salzman J, Pellizzoni L, Wirth B, Di Schiavi E, Gatti M, Artandi SE, Raffa GD. Chen L, et al. Among authors: santonicola p. Nucleic Acids Res. 2022 Nov 28;50(21):12400-12424. doi: 10.1093/nar/gkac659. Nucleic Acids Res. 2022. PMID: 35947650 Free PMC article.
A new Caenorhabditis elegans model to study copper toxicity in Wilson disease.
Catalano F, O'Brien TJ, Mekhova AA, Sepe LV, Elia M, De Cegli R, Gallotta I, Santonicola P, Zampi G, Ilyechova EY, Romanov AA, Samuseva PD, Salzano J, Petruzzelli R, Polishchuk EV, Indrieri A, Kim BE, Brown AEX, Puchkova LV, Di Schiavi E, Polishchuk RS. Catalano F, et al. Among authors: santonicola p. Traffic. 2024 Jan;25(1):e12920. doi: 10.1111/tra.12920. Epub 2023 Oct 27. Traffic. 2024. PMID: 37886910
Synthesis and Characterization of a Biocompatible Nanoplatform Based on Silica-Embedded SPIONs Functionalized with Polydopamine.
Romano M, González Gómez MA, Santonicola P, Aloi N, Offer S, Pantzke J, Raccosta S, Longo V, Surpi A, Alacqua S, Zampi G, Dediu VA, Michalke B, Zimmerman R, Manno M, Piñeiro Y, Colombo P, Di Schiavi E, Rivas J, Bergese P, Di Bucchianico S. Romano M, et al. Among authors: santonicola p. ACS Biomater Sci Eng. 2023 Jan 9;9(1):303-317. doi: 10.1021/acsbiomaterials.2c00946. Epub 2022 Dec 9. ACS Biomater Sci Eng. 2023. PMID: 36490313
αS1-Casein-Loaded Proteo-liposomes as Potential Inhibitors in Amyloid Fibrillogenesis: In Vivo Effects on a C. elegans Model of Alzheimer's Disease.
Paterna A, Santonicola P, Di Prima G, Rao E, Raccosta S, Zampi G, Russo C, Moran O, Manno M, Di Schiavi E, Librizzi F, Carrotta R. Paterna A, et al. Among authors: santonicola p. ACS Chem Neurosci. 2023 Nov 1;14(21):3894-3904. doi: 10.1021/acschemneuro.3c00239. Epub 2023 Oct 17. ACS Chem Neurosci. 2023. PMID: 37847529 Free PMC article.
Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy.
Hensel N, Cieri F, Santonicola P, Tapken I, Schüning T, Taiana M, Pagliari E, Joseph A, Fischer S, Heidrich N, Brinkmann H, Kubinski S, Bergmann AK, Richter MF, Jung K, Corti S, Di Schiavi E, Claus P. Hensel N, et al. Among authors: santonicola p. Proc Natl Acad Sci U S A. 2021 May 4;118(18):e2007785118. doi: 10.1073/pnas.2007785118. Proc Natl Acad Sci U S A. 2021. PMID: 33931501 Free PMC article.
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