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Page 1
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1.
Iacono A, Pompa A, De Marchis F, Panfili E, Greco FA, Coletti A, Orabona C, Volpi C, Belladonna ML, Mondanelli G, Albini E, Vacca C, Gargaro M, Fallarino F, Bianchi R, De Marcos Lousa C, Mazza EM, Bicciato S, Proietti E, Milano F, Martelli MP, Iamandii IM, Graupera Garcia-Mila M, Llena Sopena J, Hawkins P, Suire S, Okkenhaug K, Stark AK, Grassi F, Bellucci M, Puccetti P, Santambrogio L, Macchiarulo A, Grohmann U, Pallotta MT. Iacono A, et al. Among authors: santambrogio l. EMBO Rep. 2020 Dec 3;21(12):e49756. doi: 10.15252/embr.201949756. Epub 2020 Nov 7. EMBO Rep. 2020. PMID: 33159421 Free PMC article.
A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells.
Mondanelli G, Bianchi R, Pallotta MT, Orabona C, Albini E, Iacono A, Belladonna ML, Vacca C, Fallarino F, Macchiarulo A, Ugel S, Bronte V, Gevi F, Zolla L, Verhaar A, Peppelenbosch M, Mazza EMC, Bicciato S, Laouar Y, Santambrogio L, Puccetti P, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: santambrogio l. Immunity. 2017 Feb 21;46(2):233-244. doi: 10.1016/j.immuni.2017.01.005. Epub 2017 Feb 14. Immunity. 2017. PMID: 28214225 Free PMC article.
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation.
Mondanelli G, Coletti A, Greco FA, Pallotta MT, Orabona C, Iacono A, Belladonna ML, Albini E, Panfili E, Fallarino F, Gargaro M, Manni G, Matino D, Carvalho A, Cunha C, Maciel P, Di Filippo M, Gaetani L, Bianchi R, Vacca C, Iamandii IM, Proietti E, Boscia F, Annunziato L, Peppelenbosch M, Puccetti P, Calabresi P, Macchiarulo A, Santambrogio L, Volpi C, Grohmann U. Mondanelli G, et al. Among authors: santambrogio l. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3848-3857. doi: 10.1073/pnas.1918215117. Epub 2020 Feb 5. Proc Natl Acad Sci U S A. 2020. PMID: 32024760 Free PMC article.
3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.
Clement CC, D'Alessandro A, Thangaswamy S, Chalmers S, Furtado R, Spada S, Mondanelli G, Ianni F, Gehrke S, Gargaro M, Manni G, Cara LCL, Runge P, Tsai WL, Karaman S, Arasa J, Fernandez-Rodriguez R, Beck A, Macchiarulo A, Gadina M, Halin C, Fallarino F, Skobe M, Veldhoen M, Moretti S, Formenti S, Demaria S, Soni RK, Galarini R, Sardella R, Lauvau G, Putterman C, Alitalo K, Grohmann U, Santambrogio L. Clement CC, et al. Among authors: santambrogio l. Nat Commun. 2021 Jul 21;12(1):4447. doi: 10.1038/s41467-021-24785-3. Nat Commun. 2021. PMID: 34290243 Free PMC article.
Age-related oxidative stress compromises endosomal proteostasis.
Cannizzo ES, Clement CC, Morozova K, Valdor R, Kaushik S, Almeida LN, Follo C, Sahu R, Cuervo AM, Macian F, Santambrogio L. Cannizzo ES, et al. Among authors: santambrogio l. Cell Rep. 2012 Jul 26;2(1):136-49. doi: 10.1016/j.celrep.2012.06.005. Epub 2012 Jul 12. Cell Rep. 2012. PMID: 22840404 Free PMC article.
The lipid kinase PI4KIIIβ preserves lysosomal identity.
Sridhar S, Patel B, Aphkhazava D, Macian F, Santambrogio L, Shields D, Cuervo AM. Sridhar S, et al. Among authors: santambrogio l. EMBO J. 2013 Feb 6;32(3):324-39. doi: 10.1038/emboj.2012.341. Epub 2012 Dec 21. EMBO J. 2013. PMID: 23258225 Free PMC article.
Oxidative stress, inflamm-aging and immunosenescence.
Cannizzo ES, Clement CC, Sahu R, Follo C, Santambrogio L. Cannizzo ES, et al. Among authors: santambrogio l. J Proteomics. 2011 Oct 19;74(11):2313-23. doi: 10.1016/j.jprot.2011.06.005. Epub 2011 Jun 21. J Proteomics. 2011. PMID: 21718814 Review.
253 results